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经典恒温法测定荆芥饮片有效期 被引量:12

Determination of effective time of Schizonepeta tenuifalia pieces by classical constant temperature acceleration experiment
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摘要 目的:进行荆芥饮片有效期的研究。方法:采用经典恒温法试验,推导出荆芥挥发油和胡薄荷酮含量变化的规律,根据Arrhenius指数定律,求出20℃时的反应速度常数,计算出有效期。结果:经典恒温试验测得荆芥挥发油及胡薄荷酮含量变化符合一级反应规律,在阴凉处贮存,挥发油含量变化的速率常数K20℃为8.453 4×10-6,胡薄荷酮含量变化的速率常数K20℃为3.39×10-5,以挥发油含量为指标,该批荆芥的有效期t0.9为2.08年,以胡薄荷酮为指标,其有效期是190 d。结论:用经典恒温试验可预测荆芥饮片以挥发油含量为指标其有效期在2年左右,以胡薄荷酮为指标,其有效期为190 d。 Objective: To study the validity of Schizonepeta tenuifalia pieces. Method: The change principle for the contents of essential oil and pulegone was determined by the way of classical constant temperature acceleration experiment, and the reacting speed at 20 ℃ was calculated according to Arrhenius index law and effective time was calculated. Result: In classical constant temperature experiment, the content change of essential oil with the regular pattern of one level. The effective time of S. tenuifalia pieces stored in 20 ℃ was 2.08 years and the constant of speed is 8. 453 4 × 10 ^-6 carried out by essentioloil, 190 days with the constant of speed is 3.39 × 10^-5 carried out by pulegone. Conclusion: The effective time of S. tenuifalia pieces was about 2 years carried out by essential oil and 190 days carried out by pulegone by the way of classical constant temperature experiment.
出处 《中国中药杂志》 CAS CSCD 北大核心 2012年第21期3173-3175,共3页 China Journal of Chinese Materia Medica
基金 河南省科技厅重点项目(122102310272)
关键词 荆芥 经典恒温试验 挥发油 有效期 Schizonepeta tenuifalia classical constant temperature experiment essential oil stable life
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