摘要
目的:探讨脑梗塞后痴呆型血管性认知功能损害与血Hcy、hs-CRP浓度的相关性。方法:选择120例急性脑梗塞患者分为两组,A组:伴有痴呆型血管性认知功能损害48例;B组:无痴呆型血管性认知功能损害72例;另选择健康健康体检人120例为C组。在入院后第2天对3组患者进行血Hcy和hs-CRP检测,同时应用MoCA量表进行认知功能损害评定。结果:A组与B组的Hcy和hs-CRP浓度明显高于C组(P<0.05),同时A组也高于B组(P<0.05)。A组患者血Hcy和hs-CRP浓度与MoCA评分呈负相关,血hs-CRP浓度与MoCA评分呈负相关(P<0.05)。血Hcy和hs-CRP浓度升高与认知功能损害密切相关(P<0.05)。结论:脑梗塞后痴呆型血管性认知功能损害为老年人群的高发疾病,血Hcy和hs-CRP浓度在脑梗塞后痴呆型血管性认知功能损害患者中明显增高,是独立的危险因素。
Objective To investigate the relation between blood Hcy, hs-CRP levels and dementia vascular cognitive impairment after cerebral infarction. Methods Selected 120 cases of acute cerebral infarction （associated with vascular cognitive damage Were 48 cases, group A; associated with vascular cognitive damage were 72 cases, group B） and the healthy people of 120 cases （group C）, all cases were detected the blood Hcy and hs-CRP levels, were applicated MoCA scale assessment of cognitive impairment. Results The levels of cy and hs-CRP of group A and B were significantly higher than the group C（P〈0.05）, while the group A were higher than in group B（P〈0.05）. The blood Hcy and hs-CRP levels in group A was negatively correlated with MoCA score（P〈0.05）. Conclusion Dementia vascular cognitive impairment after cerebral infarction is high incidence of disease in the elderly, the blood Hcy and hs-CRP were significantly higher that were independent risk factors.
出处
《中国美容医学》
CAS
2012年第08X期39-40,共2页
Chinese Journal of Aesthetic Medicine
