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保留膀胱髂内动脉化疗治疗膀胱癌的疗效观察 被引量:3

Curative effect observation on retained bladder internal iliac artery chemotherapy treatment for bladder cancer
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摘要 目的探讨保留膀胱手术联合髂内动脉化疗治疗膀胱癌的疗效。方法以保留膀胱手术后联合髂内动脉化疗治疗的45例膀胱癌患者为试验组,应用保留膀胱手术结合常规膀胱灌注化疗的40例患者作为对照组,对比两组患者疗效。结果试验组患者生存质量改善情况明显优于对照组,复发率、死亡率、骨髓抑制副作用均明显低于对照组,两组间比较差异均有统计学意义(P<0.05)。结论保留膀胱手术联合髂内动脉化疗治疗膀胱癌疗效较好,有较高的临床应用价值。 Objective To explore the efficacy of retained bladder surgery combined with internal iliac arterial chemotherapy treatment for bladder cancer.Methods Forty-five cases of patients with bladder cancer treated with retained bladder surgery combined with internal iliac arterial chemotherapy were seted as experimental group,40 cases of patients with bladder cancer treated with retained bladder surgery combined with conventional infusion chemotherapy were seted as con trol group,the efficacy of two groups was compared.Results The quality of life improvement in experimental group was significantly better than that of control group,the relapse rate,mortality,bone marrow suppression side effects were significantly lower than that of control group,there were statistically significant differences between the two groups(P 0.05).Conclusion The effect of retain bladder surgery combined with internal iliac arterial chemotherapy treatment for bladder cancer is better,with higher value of clinical application.
作者 方建龙
出处 《中国当代医药》 2012年第29期191-192,共2页 China Modern Medicine
关键词 膀胱癌 膀胱保留 髂内动脉化疗 生存质量 Bladder cancer Bladder preservation Internal iliac arterial infusion chemotherapy Quality of life
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  • 1刘卓炜,周芳坚,余绍龙,秦自科,韩辉,王斌,王欢,李永红.动脉化疗治疗低分化膀胱移行细胞癌的初步临床疗效[J].癌症,2004,23(z1):1517-1519. 被引量:4
  • 2侯建国,杨波,孙颖浩,万蓬.浸润性膀胱癌患者的保留膀胱综合治疗[J].临床泌尿外科杂志,2004,19(10):619-620. 被引量:12
  • 3石梅海,蔡文清.经尿道电切加化疗治疗膀胱癌[J].中华泌尿外科杂志,1993,14(2):111-112. 被引量:8
  • 4Dimitrios P, Melina P, Maria N. Adjuvant and Neoadjuvant Chemotherapy inMuscle Invasive Bladder Cancer : Literature Review[J]. European Urology, 2005,48 60-68.
  • 5Ken-Ichi M, Koichiro N, Mitsuru N, etal. Long-term follow up of patients with invasive bladder carcinoma receiving combined cisplatin-based intra-arterial chemotherapy and radiotherapy[J]. International Journal of Urology, 2007, 14:591-594.
  • 6Advanced Bladder Cancer(ABC) Meta-analysis Collaboration. Neoadjuvant chemotherapy in invasive bladder cancer: a systematic review and metaanalysis[J]. Lancet, 2003, 361:1927--1934.
  • 7Advanced Bladder Cancer(ABC) Meta-analysis Collaboration. Neo-adjuvant chemotherapy in invasive bladder cancer update of a systematic review and meta-analysis of individual patient data[J]. Eur Urol, 2005, 48:202-205.
  • 8Grossman H B, Natale R B, Tangen C M, etal. Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer [J]. NEnglJ Med, 2003, 349: 859--866.
  • 9Shipley W U, Kaufman D S, Tester W J, et al. Radiation Therapy Oncology Group. Overview of bladder cancer trials in the Radiation Therapy Oncology Group [J]. Cancer, 2003, 97(8 suppl): 2115--2119.
  • 10Sternberg C N, Pansadoro V, Calabro F, et al. Can patient selection for bladder preservation be based on response to chemotherapy[J]? Cancer, 2003, 97:16444-16452.

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  • 1吴小鹏,陆曙炎,蔡雷铭,邹建纲,周忠兴,关乃富,陈仰之,陈静.灌注化疗前后P_(53)、bcl-2和血管内皮生长因子在浸润性膀胱肿瘤中的表达[J].北京医学,2005,27(4):222-224. 被引量:2
  • 2李道兵,罗旭,李春鸣,刘华庆,付逆.微血管密度和VEGF在膀胱癌中的表达及意义[J].华西医学,2006,21(2):237-238. 被引量:2
  • 3吴阶平.吴阶平泌尿外科学[M].山东科学技术出版社,2004,1:1059-1091
  • 4Jemal A,Siegel R, Ward E,et al.Cancer statistics,2009[J].CA Cancer J Clin,20{19, a(4) 4).
  • 5Zhong H,De Marzo AM,Laughner E,et al.Overexpression of hypoxia- inducible factor 1alpha in common human cancers and their metastases[J].Cancer Res,1999,59:5830-5835.
  • 6Bachtiary B, Schindl M, Potter R, et al.Overexepression of hypoxia-inducible factor 1alpha indicates diminished response to radiotherapy and unfavorable prognosis in patients receiving radical radiotherapy for cervical cancer [Jl.Clin Cancer Res,2003,9:2234-2240.
  • 7Bryan RT, Zeegers MP, James ND, et al.Biomarkers in bladder cancerJ].BJU Int, 2010,105(5):608-613.
  • 8LI TJ, Browne RaM, Matthews JB. Epithelial cell proliferation in odontogenickeratocysts: a comparative.imnmnocytochemical study of Ki67 in simple, recurrent and basal cell naevus syndrome (BCNS)-associated lesions [J].J Oral Pathol Med, 1995, 24 (5):221-226.
  • 9Scott RJ, Hail PA, Haldane JS,et al.A comparison of immunohistoehemieal markers of cell proliferation with experimentally determined growth fi'action [J]J Pathol,1991,165(2) : 173-178.
  • 10Onozawa M, Miyanaga N, Hinotsu S, et al. Analysis of Intravesical Recurrence After Bladder-preserving Therapy for Muscle-invasive Bladder Cancer[J].Jpn J Clin 0ncol.2012 ,Sep,42(9):825-30.

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