摘要
目的:观察腹腔镜术后辅助GnRH-a治疗子宫内膜异位症的临床疗效,探讨治疗子宫内膜异位症的最佳治疗方案。方法:选择采用腹腔镜治疗术后确诊为子宫内膜异位症患者185例,按照自愿的原则分为对照组与观察组,对照组90例术后未采用辅助治疗,观察组95例术后辅助GnRH-a治疗12个月后比较两组患者治疗前后生殖激素水平变化、临床疗效及妊娠率。结果:治疗12个月后,两组患者生殖激素水平、临床疗效方面比较差异有统计学意义(P<0.05),而妊娠率两组间差异无统计学意义(P>0.05)。结论:腹腔镜治疗子宫内膜异位症后辅助GnRH-a治疗,可提高临床疗效、减少复发,但不能提高妊娠率。
Objective：To observe the clinical efficacy of gonadotropin releasing horm one agonist（GnRH-a） in treatment of endometriosis after laparoscopic surgery.Methods： Total of 185 cases diagnosed as endometriosis definitely after laparoscopic surgery were selected and divided into control group and observation group according to the principle of voluntariness,90 cases in control group did not received adjuvant therapy,95 cases in observation group were treated with GnRH-a for 12 months after laparoscopic surgery,then the changes of reproductive hormones levels,clinical efficacies and the rate of pregnancy in the two groups were compared.Results： After treatment for 12 months,there was significant difference in reproductive hormones levels and clinical efficacy between the two groups（P〈0.05）,but there was no significant difference in the rate of pregnancy（P〈0.05）.Conclusion： Laparoscopic surgery combined with GnRH-a is effective,which may reduce the recurrence rate of endometriosis.
出处
《现代肿瘤医学》
CAS
2012年第11期2387-2389,共3页
Journal of Modern Oncology
