期刊文献+

RACK1基因过表达对子宫颈癌细胞增殖的影响 被引量:4

原文传递
导出
摘要 世界范围内,宫颈癌是第二常见的女性恶性肿瘤,其发病率仅次于乳腺癌,病死率却居女性恶性肿瘤之首。宫颈癌的侵袭性很强,常向周边组织器官侵袭性转移蔓延,且手术切除后盆腔内复发的概率高达70%。因此,宫颈癌对女性健康的威胁不容小觑。目前,宫颈癌的诊断缺乏特异性的分子标志物。
出处 《中华妇产科杂志》 CAS CSCD 北大核心 2012年第10期788-790,共3页 Chinese Journal of Obstetrics and Gynecology
  • 相关文献

参考文献20

  • 1Arbyn M, Castellsague X, de Sanjose S, et al. Worldwide burden of cervical cancer in 2008. Ann Oncol, 2011, 22:2675-2686.
  • 2Isacson CK, Lu Q, Karas RH, et al. RACK1 is a BKCa channel binding protein. Am J Physiol Cell Physiol, 2007, 292: 1459- 1466.
  • 3Berns H, Humar R, Hengerer B, et al. RACK1 is up-regulated in angiogenesis and human carcinomas. FASEB J, 2000, 14: 2549-2558.
  • 4Mamidipudi V, Zhang J, Lee KC, et al. RACK1 regulates G1/S progression by suppressing Src kinase activity. Mol Cell Biol, 2004, 24:6788-6798.
  • 5Ron D, Chen CH, Caldwell J, et al. Cloning of an intraeellular receptor for protein kinase C : a homolog of the beta subunit of G proteins. Proc Natl Acad Sci U S A, 1994, 9l :839-843.
  • 6Walboomers JM, Jacobs MV, Manos MM, et al. Human papillomavirus is a necessary cause of invasive cervical eanccr worldwide. J Pathol, 1999, 189 : 12-19.
  • 7McCahill A, Warwicker J, Bolger GB, et al. The RACK1 scaffold protein: a dynamic cog in cell response mechanisms. Mol Pharmacol, 2002. 62 : 1261-1273.
  • 8Wang Z, Zhang B, Jiang L, et al. RACKI, an excellent predictor for poor clinical outcome in oral squamous carcinoma, similar to Ki67. Eur J Cancer, 2009, 45:490-496.
  • 9Wang Z, Jiang L, Huang C, et al. Comparative proteomics approach to screening of potential diagnostic and therapeutic targets for oral squamous cell carcinoma. Mol Cell Proteomics, 2008, 7 : 1639-1650.
  • 10Blake RA, Broome MA, Liu X, et al. SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling. Mol Cell Biol, 2000, 20:9018-9027.

同被引文献23

引证文献4

二级引证文献14

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部