摘要
目的 :对照观察中药补阳还五汤治疗恢复期脑梗塞的临床疗效并探讨其机理。方法 :随机分为中药组 (补阳还五汤 ) 5 7例和西药组 (低右丹参 ) 38例 ,检测血液流变学指标、过氧化物脂质 (LPO)和超氧化物歧化酶 (SOD)变化情况并作对照分析。结果 :中药组愈显率显著高于西药组 (6 8.4%vs34.2 % ;χ2 =9.43 ,P <0 .0 1) ,且对血液流变性、LPO及SOD均有显著改善作用 (P <0 0 1) ;西药组仅有显著改善血液流变性作用 (P <0 0 5 ) ,而对LPO及SOD水平无显著改善作用。结论 :对脑梗塞恢复期的治疗 ,中药组疗效显著优于西药组 ,其机理可能是对血液流变性。
Objective:To observe clinical effects of Buyang Huanwu Decoction in treating convalescent cerebral infarction and explore the mechanism.Methods:95 cases were randomly divided into Materia Medica group(MMg)(Buyang Huanwu Decoction,n=57)and western medicine group(wmg)(Dextran 40+injection of Salviae Miltiorrhizae Co,n=38),and patients index of hemorheology,Lipid Peroxide(LPO) and Superoxide Dismutase (SOD) were tested and analysed in control.Results:the marked effective and curative rate of MMg was obviously higher than that of wmg(68.4% vs 34.2%,χ2=9.43,P<0.01). MMg had better action on improving the disorder of hemorheology (in MMg P<0.01;wmg P<0.05) and LPO & SOD(MMg P<0.01;wmg no effect).Conclusions:MMg could significantly improve the disorder of hemorheology, LPO & SOD in patients with convalescent cerebral infarction and by this mechanism it has got better clinical results than that wmg has.
出处
《四川省卫生管理干部学院学报》
2000年第2期94-95,共2页
Journal of Sichuan Continuing Education College of Medical Sciences
关键词
脑梗塞
补阳还五汤
血液流变学
中医药疗法
Cerebral infarction
Buyang Huanwu decoction
Hemorheology
Lipid peroxide
Superoxide dismutase
