摘要
目的观察生长抑素治疗单纯性肠梗阻的临床疗效。方法将到本院就治的52例单纯性肠梗阻患者随机分为两组,对照组22例给予常规治疗,治疗组30例在常规治疗基础上给予生长抑素治疗,观察两组治疗效果。结果治疗组、对照组治疗总有效率分别为100.00%、72.27%,治疗组治疗效果明显高于对照组(P<0.05);治疗组治疗后24 h血浆内毒素、D-乳酸含量均少于对照组(P<0.05);治疗组治疗7 d后血清TNF-α、IL-6含量均低于对照组(P<0.05)。结论生长抑素治疗单纯性肠梗阻,能稳定肠黏膜,减少并清除内毒素吸收,提高保守治疗成功率,值得临床广泛推广。
Objective To observe the clinical efficacy of somatostatin treatment of simple obstruction. Methods Randomly divided 52 cases of patients with simple obstruction which come to our hospital into two groups, 22 patients in the control group received conventional therapy, 30 patients in the treatment group received conventional therapy and somatostatin treatment,observed treatment effect. Results The treatment group and the control group total effective rate for 100.00%, 72.27%.The therapeutic effect of the treatment group was significantly higher than that in the control group（P 〈 0.05）; the 24 h plasma levels of toxins, D-lactic acid content of trealment group were less than the control group （P 〈 0.05 ）; after 7 days of treatment,serum TNF-c~,,IL-6 levels of treatment group were lower than the control group （P 〈 0.05）. Conclusion Somatostatin treatment of simple obstruction, can stabilize the intestinal mucosa, reduce and remove endotoxin absorption and improve the success rate of conservative treatment worthy of clinical widely promoted.
出处
《中国现代医生》
2012年第30期70-71,共2页
China Modern Doctor
