摘要
本文检测了４５例ＧＤ，１００例健康对照组血清ＴＮＦ－α水平，结果ＧＤ患者血清ＴＮＦ－α水平显著升高（Ｐ〈０．０１）。与其ＦＴ３，ＦＴ４，ＴＧＡＢＭ，ＴＭＡＢ水平及其甲吸率无相关性。升高的水平与病程长短和甲状腺大小有关。ＧＤ患者＾１３１Ｉ治疗前后血清ＴＮＦ－α水平无明显变化，＾１３１Ｉ治疗后不同效果组治疗前血清ＴＮＦ－α水平无明显差异。表明ＧＤ患者血清ＴＮＦ－α水平升高：ＧＤ的“功能缓解”与“
Serum TNF- α level in 45 GD Patients and 100 cases of control were studied. The results showed that the TNF- α level in GD patients was significantly higher (P<0.01)than in the controls and correlated to the course of the disease & the mass of the thyroid,but not to FT3,FT4,TGAB,TMAB levels and thyroid absorption rate of 131I. There was no difference TNF-α levels of GD patients before and after131I treatment.As well the TNF- α level did not affect treafment effectivebess.The cesults indicat that the level of TNF- α in GD is elevated.Furthermore 'func nonal moderation' and 'immuno moderation' are not synchronous.TNF- α does not affect the iodine absorption and sensitivity in patients.
出处
《重庆医科大学学报》
CAS
CSCD
2000年第1期47-49,共3页
Journal of Chongqing Medical University
