摘要
目的 研究原位肝移植治疗终末期肝病的临床效果。方法 在 5年内为 18例终末期肝病病人实施原位肝移植手术 ,其中肝炎肝硬化 15例 ,肝癌 3例。结果 手术死亡 5例 ,病死率2 7 2 %。围手术期存活 13例 (77 8% )。术后并发症 :腹腔出血 4例 ;胆瘘 2例。随访期间 2例胆瘘病人死亡 (分别于术后 6个月和 8个月 ) ,现存活 11例 (6 1 1% )生存时间均超过 5个月 ,最长 1例生存时间已 5年半。结论 肝移植手术是终末期肝病的有效治疗手段 ,减少手术并发症 ,预防肝移植术后乙肝再感染是提高手术成功率 ,保证长期生存的关键。
Objective To determine the efficacy of orthotopic liver transplantation (OLT) in treatment of end stage liver diseases. Methods From May 1994 to May 1999, 18 patients with the end stage liver diseases were treated with OLT in our department. Of the patients, 15 were with cirrhosis resulting from hepatitis B and 3 with hepatic cancer. Results Five patients died in the perioperative period (27.78%). Of the left 13 patients, 4 were reexplored because of bleeding in abdominal cavity on d 1 after operation and 2 presented with bile leak. The latter 2 died during the follow up. Other 11 patients have survived for 5 months to 5 years. Conclusions The liver transplantation is an effective means in treatment of end stage liver diseases. Reduction of complications and prevention of reinfection of hepatitis B virus after operation are critical for promoting successful rate of the operation to prolong survival time of the patients.
出处
《中华肝胆外科杂志》
CAS
CSCD
2000年第4期272-275,共4页
Chinese Journal of Hepatobiliary Surgery
关键词
原位肝移植
免疫球蛋白
拉米夫定
终末期肝病
Hepatitis B liver cirrhosis
Liver transplantation
Hepatitis B immune globulin
Lamivudine
