摘要
对1例乙型肝炎肝硬变患者实施原位肝移植术,使用UW液保存供体肝脏6小时,术中采用静脉-静脉转流。术后应用大剂量甲基强的松龙和标准剂量的环孢素A(CsA)进行免疫抑制治疗,对术后迟发性急性排斥反应使用甲基强的松龙冲击治疗,根据血中CsA浓度调整CsA用量,术后第6个月时HBsAg再度转为阳性,但目前患者一般情况良好,生活自理,肝脏功能正常。认为乙型肝炎患者施行肝移植时必须配合相应的治疗,以预防肝炎复发。
An orthotopic liver transplantation was successfully performed on an hepatitis Brelated cirrhotic patient with portal hypertension. The donor liver was preserved with UW solution for 6 hours. The venovenous bypass was introduced in the operation. The triple-drug immunosuppression was used. The episode of late acute rejection was treated with high dose steroid.The hepatitis was recurred 6 months postoperatively. However, the patient is still in a good with normal liver function. It is suggested that liver transplantation in patient with hepatitis B should be performed under the protection of adjuvant therapy to prevent the recurrence.
出处
《中华器官移植杂志》
CAS
CSCD
1996年第1期25-27,共3页
Chinese Journal of Organ Transplantation
关键词
肝脏
乙型肝炎
肝移植
Liver
Liver/transplantation
Hepatitis-B