摘要
目的 :观察应用大承气冲剂术后灌肠对肺功能的影响 ,并阐明其作用机理。 方法 :选择 6 6例腹部手术患者 ,分为中药组和常规治疗的对照组 ,分别于术前、术后 1、3、5d观测血清肿瘤坏死因子 (TNF)、一氧化氮 (NO)、胃动素 (MOT)、急性反应蛋白 (CRP)变化 ,同时应用动脉血气指标及肺功能仪测肺功能。用APACHEⅡ评分系统评估治疗前后全身状况。 结果 :感染、手术创伤造成TNF、CRP增高 ,MOT减低 ,肺功能损害 ,中药组上述指标恢复明显优于对照组 (P <0 .0 5 )。 结论 :应用大承气冲剂术后灌肠可减少腹腔感染和腹部手术后炎性介质的分泌 ,促进胃肠功能的恢复 ,减轻肺损害 。
Objective:To investigate the influence of Da Cheng Qi decoction(DCQD)on gastrointestinal and lung function after abdominal operation.Methods:66 abdominal operation cases were selected and divided into two groups randomly,treated with enema of Da Cheng Qi decoction and routine treatment respectively.The levels of serum NO,TNF,NOT,C reactive protein(CRP)were observed before and after operation(1st,3d,5th day).APACH Ⅱsystem was used to evaluate the patient's general condition.Results:lung function recovered earlier in Chinese herbs group than in the control significantly.Conclusion:The study showed that Da Cheng Qi decoction can promote enteric function recovery,decrease the release of inflammatory mediator and diminish lung injury after abdominal surgery.
出处
《中国中西医结合外科杂志》
CAS
2000年第4期237-240,共4页
Chinese Journal of Surgery of Integrated Traditional and Western Medicine
基金
天津市卫生局中医处科研课题! (Ⅱ
2
4)
吴咸中院士基金资助
