摘要
目的探讨飞秒激光LASIK手术中负压吸引对近视眼黄斑区视网膜厚度和视网膜神经纤维层（RNFL）厚度的影响。设计前瞻性对照研究。研究对象接受飞秒激光手术的近视眼患者143例（279眼）。方法采用相干光断层扫描（OCT）仪对中低度近视组（≥-6．00D）和高度近视组（〈-6．00D）患者飞秒激光LASIK手术前、手术后1周～1年进行检查，测量以黄斑中心凹为中心3mm半径内的视网膜平均厚度，以及以视盘为中心直径为3．4mm的视网膜神经纤维层厚度，并以地形图分4个区域显示。主要指标黄斑中心凹厚度及视盘周围RNFL厚度。结果术前两组间各参数比较差异均无统计学意义（P均〉0．05）。术后1年中低度近视组黄斑中心凹视网膜平均厚度为（147．2±18．3）μm；视盘鼻侧、颞侧、上方、下方的RNFL厚度分别是（62．4±15．7）μm、（94．3±20．2）μm、（136．4±17．6）μm、（131．3±21．7）μm，与术前比较差异均无统计学意义（P均〉0．05）；术后1年高度近视组黄斑中心凹视网膜平均厚度为（149．3±18．7）μm；视盘鼻侧、颞侧、上方、下方的RNFL厚度分别是（59．3±19．0）μm、（90．7±17．2）μm、（129．2±25．1）txm、（123．3±21．8）μm，与术前比较差异均无统计学意义（P均〉0．05）。结论飞秒激光LASIK术中吸力环负压吸引未对视网膜神经纤维层厚度造成明显影响。
Objective To investigate the influence of the negative pressure suction during femtosecond laser assisted LASIK on the maeular retinal thickness and retinal nerve fiber layer thickness in myopia eyes. Design Prospective, comparative case series. Participants One hundred and forty three myopia patients （279 eyes） were enrolled in the study. Methods The thickness of macular central fovea and retinal nerve fiber layer thickness were measured using optical coherence tomography （OCT） before and after femto second laser assisted LASIK. The myopic eyes were divided into two groups, the high myopia （〈-6.00 D） group and medium to low myopia （≥-6.00 D） group. The macular （or RNFL） scan pattern come from three 3 mm （or 3.4 mm） diameter circular scans centered on maeular central fovea （or the optic nerve head ） acquired in rapid succession. Main Outcome Measures Macular and RNFL thickness. Results Before surgery there were no statistical difference between the two groups （P〉0.05）. After 1 year, in the low and medium myopia group and the high myopia group, the average thickness of fovea and average RNFL thickness in superior, nasal, inferior, and temporal were （147.2 ±18.3）μm, （62.4±15.7）μm, （94.3± 20.2）μm, （136.4±17.6）μm, （131.3 ±21.7）μm; （ 149.3±18.7）μm, （59.3 ±19.0）μm, （90.7±17.2）μm, （129.2±25.1）μm, （123.3±21.8）μm respectively. None of the macular thickness and RNFL thickness parameters were found to have a significant change between preoperation and 1 year after surgery. Conclusions Negative pressure suction during femtosecond laser LASIK dont＇t significantly affect the macular retinal thickness and RNFL thickness parameters postoperatively.
出处
《眼科》
CAS
2012年第5期340-343,共4页
Ophthalmology in China
关键词
飞秒激光
近视
视网膜厚度
视网膜神经纤维层
femtosecond laser
myopia
retinal thickness
retinal nerve fiber layer
