尼莫地平联合法舒地尔治疗颅内动脉瘤术后脑血管痉挛的效果观察被引量：6

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摘要目的探讨尼莫地平联合盐酸法舒地尔治疗颅内动脉瘤术后脑血管痉挛的临床效果。方法将66例显微外科手术或血管内介入治疗的颅内动脉瘤患者随机分为观察组和对照组各33例,观察组应用尼莫地平联合法舒地尔治疗,对照组单用尼莫地平,比较两组患者经颅脑多普勒超声大脑中动脉血流平均速度、CT、神经功能缺损程度等指标的差异。结果①两组患者用药7d和14d脑彩超大脑中动脉血流平均速度(MCA)均较治疗前显著降低,两组间比较差异不显著。②观察组治疗后7dCT扫描发现7例患者出现新梗塞,对照组有6例出现新梗塞,用药14d后两组患者脑梗死均消失。③两组神经功能缺损程度比较,两组患者脑血管痉挛发生率均较治疗前显著下降,观察组总有效率96.36%,对照组总有效率90.91%。结论尼莫地平联合法舒地尔和单用尼莫地平均可有效缓解颅内动脉瘤术后患者脑血管痉挛,明显改善患者预后,联合用药组比单用尼莫地平组效果稍好,但两组比较疗效无显著性差异。

作者刘岩

机构地区吉林省吉林市中心医院

出处《中国实用医药》 2012年第27期198-199,共2页 China Practical Medicine

关键词尼莫地平法舒地尔颅内动脉瘤脑血管痉挛疗效抱歉系统响应超时请稍后再试

分类号 R743.3 [医药卫生—神经病学与精神病学]

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