摘要
本文测定健康人66例,胃癌、肺癌、肝癌病人共64例的红细胞膜唾液酸和岩藻糖含量。发现健康人上述两项指标没有性别和年龄的差异。与健康组比较,各癌症组红细胞膜唾液酸显著增多(p<0.001),而岩藻糖显著减少(p<0.001),但含量较分散、与健康者重叠较大。红细胞膜唾液酸与岩藻糖之比、各癌症组都高于健康组(p<0.001);以高于健康组M+2SD 者为阳性,则胃癌组、肺癌组和肝癌组的阳性率分别为79.2％,95.0％和80.0％,对肿瘤理论研究和临床诊断颇有价值。
The level of sialic acid and fucose in red cell membrane in 66 healthy adults and 64 patients with stomach cancer、lung cancer and hepatoma were determined. The levels of sialic acid and fucose in health adults were no different between both;two sex groups and in four years groups.In comparison with the healthy group,the levels of sialic acid in patients with several cancer groups were markedlyelevatcd(p<0.001),but the levels of fucose in patients in several cancer groups were markedly reduced(p<0.001).Therefore the ratio of sialic acid and fueose(S/F)in red cell membrane of several cancer groups were markedly elevated in significant difference from the S/F of the healthy group(p<0.001).If the S/F exceeded M+2SD in the healthy group,they could be taken as positive.The positive rates of stomach cancer、lung cancer and hepatoma groups were 79.2%、 95.00/00 and 80.0% respectively.These results show that the determination of S/F in red cell membrane might be value in cancer research and have clinical application.
出处
《江南大学学报（自然科学版）》
CAS
1990年第2期139-142,共4页
Joural of Jiangnan University (Natural Science Edition)
关键词
唾液酸
岩藻糖
红细胞膜
胃癌
肺癌
肿瘤病
Sialic acid
Fucose
Red cell membrane
Stomach cancer
Lung cancer
Hepatoma
