摘要
目的 探讨晚期妊娠孕妇血清β-HCG和妊高征的关系。方法 对 3 0例妊高征孕妇 (研究组 )和 2 4 6例正常孕妇 (对照组 ) ,采用放射免疫法测定静脉血清中β-HCG和 E3 含量。结果 1中、重度妊高征患者血清β-HCG含量明显高于对照组 ,差异有显著性 ( P<0 .0 5) ;2各组间血清 E3 水平比较差异无显著性 ,但随着妊高征程度的加重 E3 有逐渐降低的趋势。结论 β-HCG的增高在妊高征的发病中有重要意义 。
Objective To investigate the relationship between maternal serum β human chorionic gonadotropin(β HCG) levels in late pregnancy and pregnancy induced hypertention(PIH).Method Levels of serum β HCG and E 3 were determined by radioimmunoassay in 30 PIH patients(study group) and 246 normal pregnant women(control group).The study group was further divided into three groups:mild PIH patients(10 cases),moderate PIH patients(9 cases) and severe PIH patients(11 cases).Result The levels of serum β HCG in moderate and severe PIH patients were significantly higher than those of in mild PIH patients and normal pregnant women(P<0.05);The levels of serum E 3 showed no significant difference among the four groups,but the levels of serum E 3 decreased gradually with PIH increasing the severity of disease.Conclusion The increase of serum β HCG in PIH patients can play an important role in the pathophysisological changes in PIH.The β HCG can be a diagnosing index of PIH. [
出处
《潍坊医学院学报》
2000年第2期92-93,共2页
Acta Academiae Medicinae Weifang
关键词
绒毛膜促性腺激素
雌三醇
妊高征
测定
Pregnancy complications,cardiovascular
Gonadotropin,chorionic
Estriol