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妊娠高血压综合征血清β-HCG与E_3的测定及意义 被引量:3

The Clinical Evaluation and the Determination of Levels of Maternal Serum β-HCG and E_3 in Late Pregnancy Hypertention
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摘要 目的 探讨晚期妊娠孕妇血清β-HCG和妊高征的关系。方法 对 3 0例妊高征孕妇 (研究组 )和 2 4 6例正常孕妇 (对照组 ) ,采用放射免疫法测定静脉血清中β-HCG和 E3 含量。结果  1中、重度妊高征患者血清β-HCG含量明显高于对照组 ,差异有显著性 ( P<0 .0 5) ;2各组间血清 E3 水平比较差异无显著性 ,但随着妊高征程度的加重 E3 有逐渐降低的趋势。结论 β-HCG的增高在妊高征的发病中有重要意义 。 Objective To investigate the relationship between maternal serum β human chorionic gonadotropin(β HCG) levels in late pregnancy and pregnancy induced hypertention(PIH).Method Levels of serum β HCG and E 3 were determined by radioimmunoassay in 30 PIH patients(study group) and 246 normal pregnant women(control group).The study group was further divided into three groups:mild PIH patients(10 cases),moderate PIH patients(9 cases) and severe PIH patients(11 cases).Result The levels of serum β HCG in moderate and severe PIH patients were significantly higher than those of in mild PIH patients and normal pregnant women(P<0.05);The levels of serum E 3 showed no significant difference among the four groups,but the levels of serum E 3 decreased gradually with PIH increasing the severity of disease.Conclusion The increase of serum β HCG in PIH patients can play an important role in the pathophysisological changes in PIH.The β HCG can be a diagnosing index of PIH. [
出处 《潍坊医学院学报》 2000年第2期92-93,共2页 Acta Academiae Medicinae Weifang
关键词 绒毛膜促性腺激素 雌三醇 妊高征 测定 Pregnancy complications,cardiovascular Gonadotropin,chorionic Estriol
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  • 1朱丹,刘玉萍,蔡知天,冯莉.多普勒超声检测妊高征患者母体循环血流动力学对围产儿结局的诊断价值[J].吉林大学学报(医学版),2005,31(3):442-445. 被引量:3
  • 2宋一丽,徐荣春,覃建庆.妊娠晚期孕妇血hCG、HPL及hCG/HPL异常与不良妊娠结局关系的研究[J].临床误诊误治,2006,19(10):56-57. 被引量:4
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