摘要
目的提高对米勒-费舍尔综合征诊断与治疗的认识。方法回顾分析2007年3月-2012年3月6例米勒-费舍尔综合征的临床资料,结合国内外报道及研究进展,探讨对米勒-费舍尔综合征的再认识。结果 6例米勒-费舍尔综合征患儿中共济失调6例,表现为步态不稳、指鼻不准,甚至不能行走,球麻痹3例,表现为饮水呛咳,声调下降,言语不清,眼肌麻痹6例,表现为眼球运动受限,部分上睑下垂,部分眼球震颤,腱反射消失6例表现为膝腱反射、跟腱反射消失;头颅CT或MRI正常6例,脑脊液蛋白-细胞分离6例,电生理检查提示周围神经损害6例。结论米勒-费舍尔综合征是格林-巴利综合征的变异型,眼肌麻痹、共济失调、腱反射消失是其主要特点,多伴有脑脊液蛋白-细胞分离和周围神经损害,预后良好。
Objective To improve the understanding about diagnosis and treatment of Miller-Fisher syndrome （MFS）. Methods Retrospective analysis of clinical data of 6 children with MFS were conducted, and combined with the documents con- cerned, to explore for further understanding of MFS. Results Among the six children, six were of ataxia, three patients bulbar palsy, six ophthalmoplegia, six areflexia, six CT or MRI normal. CSF aibum inocytological dissociation was present in six cases, six peripheral nerve lesions were presented on electrophysiology. Conclusion MFS was a localized variant of Guillain-Barre syn- drome, characterized by ophthalmoplegia, areflexia, ataxia, CSF aibum inocytological dissociation, peripheral nerve lesions, good outcome.
出处
《中华全科医学》
2012年第11期1683-1684,共2页
Chinese Journal of General Practice
