摘要
随着生物科学技术的不断发展,微生物转化逐渐应用于天然产物的研究中。本文简介了微生物转化反应的专一有效、反应条件温和、收率高等特点,对近5年来微生物转化在天然产物研究中的应用进行了综述,重点综述了微生物对蒽醌类、黄酮类、萜类、甾体类、生物碱类和苷类化合物的生物转化,并对其发展前景进行了展望。
With the continuous development of biotechnology technology,microbial transformation gradually was applied to the study of natural products.The specific effective reactions,mild reaction conditions and high yield of the microbial transformation were outlined in this paper.The applications were reviewed in the microbial transformation of natural products in recent five years,especially in anthraquinones,flavonoids,terpenoids,steroids,alkaloids and glycosides.The developments of microbial transformation were prospected.
出处
《药学实践杂志》
CAS
2012年第5期321-325,共5页
Journal of Pharmaceutical Practice
关键词
微生物转化
天然产物研究
应用
microbial transformation
natural products research
applications