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右美托咪啶在腰硬联合麻醉下髋关节置换术中的应用 被引量:6

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摘要 目的:探讨盐酸右美托咪啶在腰硬联合麻醉髋关节置换术中的镇静、镇痛效应。方法:将60例择期行髋关节置换术的患者随机分为两组,A组为盐酸右美托咪啶组(30例),A组于切皮前10min静脉泵入盐酸右美托咪啶1μg/kg,持续10min后改为静脉泵入盐酸右美托咪啶0.4μg/kg,维持至手术结束前30min;B组为对照组(30例),观察并记录两组麻醉前(T0)、腰硬联合麻醉后10min(T1)、切皮后30min(T2)、切皮后60min(T3)、术毕(T4)各时点MAP、HR及Narcotrend指数(NT1)的变化,使用Ramesay法进行镇静评分。结果:A组术中HR、MAP较平稳,B组在T2时点后HR、MAP明显升高(P<0.05);A组NT1值在T2时点后呈进行性的下降(P<0.05);Ramesay评分A组在T2时点后进行性增加(P<0.05)。结论:右美托咪啶在腰硬联合麻醉髋关节置换术中具有良好的镇痛、镇静效应。
出处 《中国中西医结合外科杂志》 CAS 2012年第5期513-515,共3页 Chinese Journal of Surgery of Integrated Traditional and Western Medicine
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参考文献7

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