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变应性鼻炎血清学特异性IgE检测的结果分析 被引量:2

Serological detection of specific IgE in allergic rhinitis
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摘要 目的:调查本地区变应性鼻炎患者变应原血清特异性IgE阳性率,比较不同年龄和性别患者血清特异性IgE阳性率的差别。方法:对145例变应性鼻炎患者进行血清吸入性和食入性变应原特异性IgE检测,并将受检者按年龄及性别分组,分别进行阳性率比较。结果:145例变应性鼻炎患者变应原特异性IgE总阳性94例,阳性率64.8%。其中,单一变应原阳性45例(47.9%),两种及以上变应原阳性49例(52.1%);以吸入性变应原为主。男性与女性变应原特异性IgE阳性率比较差异无统计学意义(P>0.05);成年人与青少年阳性率比较差异有统计学意义(P<0.05)。结论:本地区变应性鼻炎患者中吸入性变应原是引起发病的主要原因,其中户尘螨粉尘螨阳性率最高,占87.4%。特异性IgE阳性率与年龄有关,青少年较成年人阳性率高。 To investigate the positive rate of allergen-specific serum IgE in local patients with aller- gic rhinitis, and compare the positive rate of allergen-specific serum IgE across different age groups and between sexes. Method:Inhalant and ingested serum allergen-specific IgE was detected in 145 patients with allergic rhinitis. Patients were grouped by age and sex, and then the positive rate was compared between the two groups. Result: Ninety-four out of 145 cases had positive allergen specific IgE, and the positive rate was 64.8%. There were 45 cases with single positive allergen, accounting for 47.9%. And there were 49 cases with two or multiple positive allergens, mainly inhalant allergens, accounting for 52.1%. The difference of allergen-specific IgE positive rate between men and women was not statistically significant(P〈0.05) ; but the positive rate between adults and ado- lescents was statistically significant(〈0.05). Conclusion:Inhalant allergen is a major cause of allergic rhinitis in local people. The positive rate of household dust mites and dermatophagoides was highest(87.4%). The positive rate of specific IgE was associated with age, and adolescents have higher positive rate than adults.
作者 开月梅
出处 《临床耳鼻咽喉头颈外科杂志》 CAS CSCD 北大核心 2012年第20期933-935,共3页 Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词 鼻炎 变应性 变应原 血清特异性IGE 流行病学 rhinitis, allergic allergens serum specific IgE epidemiology
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