摘要
目的研究超高度近视患者屈光力及眼轴影响因素,并分析超高度近视患者易发青光眼的危险因素。方法选取216例(354眼)受试者按照屈光力不同分成3组:A组260眼(>-9.00～12.00D)、B组75眼(>-12.00～15.00D)、C组19眼(>-15.00D),对其屈光力、眼轴长度(axial length,AL)、前房深度(anterior chamber depth,ACD)、前房氉角(anterior chamber angle,ACA)、中央角膜厚度(central corneal thickness,CCT)、眼压(intraocular pressure,IOP)等相关眼部参数进行测量,分析各参数之间的相互关系。结果超高度近视眼等效球镜度数(spherical equivalent,SE)与AL、角膜最大屈光力(K2)、年龄之间呈负相关(均为P<0.05),与ACD及ACA之间呈正相关(均为P<0.05)。AL与Goldmann眼压值(Goldmann-correlated IOP value,IOPg)、角膜代偿的眼压值(corneal compensated intraocular pressure,IOPcc)和年龄之间呈正相关关系(均为P<0.001),而与角膜最小屈光力(K1)、K2之间呈显著负相关关系(均为P<0.001)。IOPcc与K1、K2呈显著负相关关系(均为P<0.001);IOPg与CCT和AL呈显著正相关关系(均为P<0.001),而与K1、K2呈负相关关系(均为P<0.05)。ACD与ACA、IOPg之间,ACA与IOPg、IOPcc之间均呈正相关关系(均为P<0.05)。B组的SE与IOPcc呈显著负相关关系(P<0.01)。影响超高度近视眼屈光力的主要因素为SE、AL、K2及ACD,而影响AL的主要因素为K1、K2、IOPg及年龄。结论 AL延长是超高度近视眼发展的重要影响因素,AL越长近视越严重,而IOP可以通过影响AL而影响超高度近视眼的屈光力,从而加快超高度近视的发展。
Objective To study the factors affecting diopter and axis of super-high myopia,and investigate the risk factors of glaucoma in super-high myopia.Methods A total of 216 cases （354 eyes） were chosen,based on the diopter,all patients were divided into group A（from -9.00 D to -12.00 D,260 eyes）,group B（from -12.25 D to -15.00 D,75 eyes）and group C（less than -15.00 D,19 eyes）.The diopter,axial length （AL）,anterior chamber depth （ACD）,anterior chamber angle （ACA）,central corneal thickness （CCT）,intraocular pressure （IOP） were measured.The linear correlation among these factors was analyzed.Results The spherical equivalent （SE） of super-high myopia was negative correlated with AL,maximum of corneal diopter （K2） and age（both P0.05）,while positive correlated with ACD and ACA（both P0.05）.AL was positive correlated with Goldmann-correlated IOP （IOPg）,corneal compensated IOP （IOPcc） and age（both P0.01）,while negative correlated with minimum of corneal diopter （K1） and K2（both P0.001）.IOPcc was negative correlated with K1 and K2（both P0.001）.IOPg was positive correlated with CCT and AL（both P0.001）,while positive correlated with K1 and K2（both P0.05）.ACD was positive correlated with ACA and IOPg（both P0.05）.ACA was positive correlated with IOPg and IOPcc （both P0.05）.SE was negative correlated with IOPcc in group B（P0.01）.The significant factors affecting diopter of super-high myopia were SE,AL,K2 and ACD.The significant factors affecting axis of super-high myopia were K1,K2,IOPg and age.Conclusion The growth of AL is the most important factor for development of super-high myopia.The more long the AL,the more severe the myopia.IOP affect diopter of super-high myopia by affecting AL and speed up the development of super-high myopia.
出处
《眼科新进展》
CAS
北大核心
2012年第10期952-955,共4页
Recent Advances in Ophthalmology
基金
黑龙江省哈尔滨市科技创新人才研究专项资金项目(编号:2010RFLXS010)
哈尔滨医科大学附属第一医院科研基金(编号:G08-002)
黑龙江省人事厅留学回国人员启动基金~~
关键词
超高度近视
屈光力
眼轴长度
眼压
前房深度
原发性开角型青光眼
super-high myopia
diopter
axial length
intraocular pressure
anterior chamber depth
primary open-angle glaucoma
