摘要
目的探讨中西医结合干预对BMI≤24糖耐量减低（IGT）患者转化为糖尿病（DMl的影响。方法筛选BMI≤24社区居民152例，随机双盲分成四组（每组38例）：A组中药＋社区行为干预；B组西药＋社区行为干预；C组中药＋西药＋社区行为干预；D组单纯社区行为干预。进行口服75g葡萄糖耐量试验（OGTT），并每三个月进行静脉血测空腹血糖（FPG）和OGTT后2h血浆血糖（2hPG）检测，随访12个月。结果经药物或单纯行为干预后，A、B组干预前后各项临床观察指标显著下降（P〈0．05），C组下降极显著（P〈0．01），D组差异不明显。中西医结合社区行为干预IGT转化DM的有效率最高，达97．4％。结论中西医结合社区行为干预能有效干预BMI≤24IGT人群转化为DM。
Objective To investigate the effect of combination of traditional Chinese medicine （TCM） and western medicine in preventing and treating patients （BMI ≤ 24） with impaired glucose tolerance （IGT）. Methods 152 cases with BMI ≤ 24 were randomly divided into 4 groups, group A treated byTCM and behavioral intervention, group B treated by western medicine and behavioral intervention, group C treated by TCM, western medicine and behavioral intervention, group D treated with behavioral intervention only all cases had a 75 goral glucose tolerance test （OGqT） and checked fasting blood glucose （FPG） ＆ 2hPG every 3 months, then follow-up for 12 months. Results The correlated clinical indexes of group A and B decreased obviously after treatment（P〈 0.05） group C got best effect（P〈 0.01） but there was no clinical improvement in group D. Conclusion It is suggested that combination therapy may prevent BMI ≥ 24 patients with IGT from developing diabetes.
出处
《国际医药卫生导报》
2012年第20期2974-2977,共4页
International Medicine and Health Guidance News
基金
越秀区卫生局与科技局合作基金（2010-WS-029）
关键词
糖耐量减低
中西医结合
行为干预
防治研究
Impaired glucose tolerance
Traditional Chinese medicine and western medicine
Behavioral intervention
Prevention and treatment studies
