摘要
目的:观察高压氧联合度洛西汀综合治疗卒中后抑郁状态(PSD)的疗效。方法:将86例明确PSD患者随机分为治疗组46例和对照组40例,治疗组接受高压氧联合度洛西汀治疗,对照组接受度洛西汀冶疗,分别于治疗前,治疗后3、6个月末进行HAMD抑郁量表、神经功能缺损程度(NIHSS)和日常生活活动能力(ADL)评分。结果:两组病例在治疗前、后,HAMD评分和NIHSS评分降低,ADL评分增加(P<0.05);组间比较,3个月时两组各项评分差异无统计学意义(P>0.05),6个月时治疗组各项评分优于对照组(P<0.05)。结论:高压氧联合度洛西汀治疗能有效提高度洛西汀对PSD的疗效。
Objective ：To observe the effect of hyperbaric oxygen（HBO） combined with duloxetine in trcatment of post-stroke depression（PSD）.Methods：86 cases of clear PSD patients were randomly divided into treatment group（46 cases） and control group（40 cases）.Treatment group received therapy of HBO combined with duloxetine,control group received duloxetine therapy only.Before treatment after treatmen for 3,6 mouths with HAMD,NIHSS and ADL,respectively.Results：The scores HAMD and NIHSS were decreased and the scores of ADL were in-creased significantly in both groups after treatment（P〈0.05）.No significantly difference in scores between the two groups were found 3 months of treatment（P 〈0.05）.The reduction of the scores of HAMD and NIHSS and the increase of ADL were significantly greater in the treatment group than in the control group（P0.05）.Conclusion：HBO combined with duloxetine can improve the effect of cluloxetine to PSD.
出处
《内蒙古中医药》
2012年第18期93-93,110,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
关键词
脑卒中
卒中后抑郁
高压氧
度洛西汀
Stroke：Post-stroke depression
Hyperbaric oxygen
Duloxetine
