摘要
以二乙烯三胺和乙酸为原料,通过成环、催化脱氢和水解三步反应合成了1-氨乙基-2-甲基咪唑。通过红外光谱、核磁共振氢谱和质谱对合成物进行了表征。结果表明:在n(二乙烯三胺)∶n(乙酸)=1∶2,升温至200℃关环脱水的条件下,生成N-(2-甲基-2-咪唑啉)乙基乙酰胺,达到92.3%的产率。然后,将该咪唑啉用雷尼镍催化脱氢生成对应的咪唑,产率94.0%。最后,将N-(2-甲基-2-咪唑)乙基乙酰胺用盐酸回流水解,得到的1-氨乙基-2-甲基咪唑,产率84.8%。
1-Aminoethyl-2-methylimidazole was synthesized from diethylenetriamine and acetic acid by cyclization,catalytic dehydration and hydrolysis reaction.The chemical struction was characterized by FT-IR,1H-NMR and MS.The experiment showed that when n（diethylenetriamine）∶n（acetic acid）=1∶2,elevating temperature to 200 ℃,the product was N-（2-methyl-2-imidazolinyl）ethyl acetamide with the yield of 92.3 %.The next reaction was dehydration of imidazoline to imidazole with Raney-Ni.The yield of this reaction was 94.0 %.Finally,1-Aminoethyl-2-methylimidazole could be got by hydrolysis reaction of N-（2-methyl-2-imidazolyl）ethyl acetamide with HCL and the yield was 84.8 %.
出处
《广东化工》
CAS
2012年第14期11-12,共2页
Guangdong Chemical Industry
关键词
咪唑
固化剂
雷尼镍
脱氢
水解法
imidazole
curing agent
Raney-Ni
dehydration
hydrolysis
