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转基因动物模型在毒理学中的应用 被引量：3

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摘要 目的转基因动物模型是人类疾病研究的一个重要工具,它在毒理学中的应用也非常广泛,可以作为部分传统毒理学方法的替代试验,并具有比传统毒理学方法更广泛的研究价值。转基因动物模型在毒理学中的应用以毒理学机制研究最多,其次,在毒理学安全评价、基因功能分析等方面发挥着较大的作用,本综述主要从这三方面来阐述转基因动物模型在毒理学中的应用。
作者 张峻 综述 戴宇飞 审校
机构地区 中国疾病预防控制中心职业卫生与中毒控制所
出处 《卫生研究》 CAS CSCD 北大核心 2012年第5期868-873,共6页 Journal of Hygiene Research
基金 国家自然科学基金资助(No.81172641)
关键词 转基因动物 发病机制 安全评价 基因功能分析
分类号 R994 [医药卫生—毒理学]
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参考文献33

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二级参考文献13

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卫生研究
2012年 第5期

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