摘要
作者采用生化分析法测定血清α_1抗胰蛋白酶(A_1AT) 浓度共388例,A_1AT测定结果其中正常人170例,急性肝炎82例,慢性肝炎32例和肝内良性占位性病变17例,均无阳性。肝硬化35例及原发性肝癌52例,其A_1AT阳性率分别为2.86％(1/35),和78.84％(41/52)。在9例AFP阴性原发性肝癌中,A_1AT阳性5例,A_1AT阳性率可达55.56％(5/9)。本组资料提示A_1AT活性测定对原发性肝癌之诊断有临床应用价值。
Serum alpha-1-antitrypsin (A_1AT) levels were determined with biochemical technic in 388 cases. The positive rates of A_1AT were 2.86％ in 35 cases of hepatic cirrhosis and 78.84％ in 52 cases of primary liver cancer respectively, while the negative results were found in all the 170 healthy individuals as well as in 82 cases of acute hapatitis, 32 cases of chronic hepatitis and 17 cases of benign hepatic spaceoccupying lesion. Among 9 cases of primary liver cancer with negative AFP, 5 cases yielded positive result by A_1AT determination, which accounted for 55.56％ of this group. It is suggested from our preliminary findings that serum A_1AT determination is of value in the diagnosis of primary liver cancer.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1990年第4期233-234,共2页
Chinese Journal of Clinical Oncology
关键词
肝肿瘤
诊断
A1AT
Α1抗胰蛋白酶
Serum alpha-l-antitrypsin (A_1AT)
Primary liver cancer
Diagnosis
