摘要
目的探讨内镜下氩离子凝固术(APC)加埃索美拉唑治疗舌型及岛型SSBE疗效及安全性。方法内镜及病理检查确诊为舌型或岛型的SSBE患者45例随机分为两组,治疗组24例行内镜下APC加埃索美拉唑治疗,对照组21例单纯给予口服埃索美拉唑治疗,分别于治疗后3,6,9及12个月复查胃镜并取活检送病理检查。治疗组中复查胃镜未达显效的患者,再行镜下APC治疗并继续口服埃索美拉唑治疗4周。结果治疗组患者治疗后3,6,9及12个月总有效率均为100%,平均显效率为87.5%,与对照组(30.5%,6.1%)相比较,差异具有显著性(P<0.01);治疗组未出现出血、穿孔、食管狭窄等相关并发症。结论内镜下APC联合埃索美拉唑治疗SSBE疗程短,安全有效,并发症少。
[Objective] To study the clinical effects of endoscopic argon plasma coagulation（APC） combined with esomeprazole using for island-type and tongue-type SSBE.[Methods] 45 patients with island-type or tongue-type SSBE were randomly divided into treatment group and control group.Treatment group was treated with APC combined with esomeprazole for 4 weeks,while the control group was treated with esomeprazole only.All patients were received the endoscopic review and biopsy at 3,6,9,and 12 months.If there was no effect on the patients of the treatment group,APC and esomeprazole was repeated.[Results] The treatment group＇s total effective rate was 100% and the average effective rate was 87.5%,while the control group＇s was 30.5%and 6.1%,the difference was statistically significant（P 0.01）.All patients who received APC were no complications.[Conclusion] APC combined with esomeprazole using in SSBE is efficacy and safe,worthy of clinical promotion.
出处
《中国内镜杂志》
CSCD
北大核心
2012年第8期796-798,共3页
China Journal of Endoscopy
关键词
BARRETT食管
SSBE
舌形BE
岛形BE
氩离子凝固术
Barrett＇s esophagus
short-segment Barrett＇s esophagus
tongue-type
island-type
argon plasma coagulation
