摘要
目的:建立毛细管电泳法测定富马酸酮替芬糖浆剂中富马酸酮替芬的含量。方法:以50 mmol·L-1磷酸二氢钾缓冲液为运行缓冲液,运行电压为30 kV,检测波长为301 nm。结果:富马酸酮替芬(以酮替芬计)在16.08～80.40μg·mL-1浓度范围内有良好的线性关系(r=0.9995),回收率为100.1%(n=9)。结论:此方法可用于富马酸酮替芬糖浆剂的含量测定。
Objective：To establish a capillary electrophoretic method for determining ketotifen fumarate syrup.Methods：A capillary electrophoretic was performed with the running buffer consisted of 50 mmol·L-1 KH2PO4 at a voltage of 30 kV,and detected with a UV detector at the wavelength of 301 nm.Results：A linear relationship was observed in the range of 16.08-80.40 μg·mL-1（r=0.9995）,a average recovery of 100.1% were obtained（n=9）.Conclusion：Capillary electrophoresis can be used to determine the content of ketotifen fumarate syrup.
出处
《药物分析杂志》
CAS
CSCD
北大核心
2012年第10期1886-1888,共3页
Chinese Journal of Pharmaceutical Analysis
