摘要
目的探讨奥美拉唑、克拉霉素、阿莫西林三联疗法治疗非甾体类抗炎药(NSAIDs)相关性胃溃疡的临床疗效。方法以该院2010年4月—2011年10月长期应用非甾体抗炎药的80例风湿性疾病患者作为研究对象,所有患者均有不同程度的胃溃疡、十二指肠溃疡、复合性溃疡,将其随机分为实验组和对照组,各40例,实验组采用三联疗法,对照组单一应用奥美拉唑,观察两组疗效。结果实验组有效率为95.0%,对照组有效率为75.0%,实验组有效率明显优于对照组(P<0.05),实验组Hp根除率为92.5%,对照组为52.5%,实验组Hp根除率明显优于对照组(P<0.05)。结论奥美拉唑、克拉霉素、阿莫西林三联疗法治疗NSAIDs相关性消化性溃疡的疗效确切,安全有效,值得在临床工作中推广应用。
Objective To investigate the omeprazole,clarithromycin,and amoxicillin triple therapy for gastric ulcer of non steroidal anti-inflammatory drugs（NSAIDs） efficacy analysis.Methods 80 patients with long term use of non-steroidal anti-inflammatory drugs in patients with rheumatic diseases in April 2010 to 2011 in October as a research object,all patients had varying degrees of gastric ulcer,duodenal ulcer and complex ulcer,were randomly divided into experimental and control groups,40 cases,the experimental group were treated with triple therapy,the control group,a single application Omeprazole,observed after treatment.Results The effective rate was 95.0%,the control group was 75.0%,the experimental group than the control group（P 〈0.05）,the experimental group Hp eradication rate was 92.5%,52.5% in the control group and experimental group Hp eradication rate than the control group（P 〈0.05）.Conclusion The efficacy of omeprazole,clarithromycin,and amoxicillin triple therapy in the treatment of NSAIDs-related peptic ulcer is accurate,and safe and effective,it is worth on the application in clinical work.
出处
《中外医疗》
2012年第26期25-26,共2页
China & Foreign Medical Treatment
