摘要
为研究非甾体抗炎药 (NSAIDs)致消化性溃疡出血的临床特征。笔者对解放军第 2 10医院消化性溃疡出血住院患者的临床资料按照出血前 10天内是否服用过NSAIDs分为两组进行比较。结果显示 ,2 6 2例消化性溃疡出血患者中有 18 32 %服用过NSAIDs。两组患者的性别、消化性溃疡史、出血程度、病变大小及部位比较无显著性差异 (P >0 0 5 ) ,但NSAIDs组患者的年龄偏大 ,较多患者有消化道出血史、心血管病史 ,出血前消化道症状不明显 ,溃疡更易多发 ,平均住院天数明显减少 (P <0 0 5 )。
To study the clinical characteristics of NSAIDs induced peptic ulcer bleeding (PUB), 262 inpatients with PUB were reviewed.The patients were divided into 2 groups based on whether or not NSAIDs were taken within 10 days of the onset of bleeding.The results indicated that 48(18 32%) of 262 patients had consumed NSAIDs. There was no significant difference in the multivariate analysis between the 2 groups regarding sex of the patients, previous history of peptic ulcer, ulcer size, ulcer location and degree of bleeding ( P >0 05). NSAIDs users were older than nonusers by a mean of 12 years, and more likely to have a history of upper gastrointestinal bleeding ( P =0 010) and cardiac vessel disease( P =0 000). NSAIDs users have higher number of ulcers ( P =0 002), fewer dyspeptic symptoms ( P =0 000) and shorter hospital stay( P =0 017).
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2001年第11期852-853,共2页
Medical Journal of Chinese People's Liberation Army
关键词
非甾体抗炎药
消化性溃疡
出血
药物不良反应
nonsteroidal anti inflammatory drugs
peptic ulcer
peptic ulcer hemorrhage
