摘要
实验兔是重要的实验动物之一,在医药领域发挥重要作用。各种分子遗传标记的出现为实验兔系统发育、种群遗传结构分析以及质量控制等各个领域提供了更为简便、可靠的研究手段。但目前,国内实验兔遗传质量不稳定,遗传背景不明确,严重制约着实验兔的应用。本文对各种分子标记在兔遗传多样性中的应用进行综述,以为实验兔遗传检测方法的建立提供帮助。
Experimental rabbits, one of the most important experimental animals,played an imptant role in medical field. All kinds of genetic markers methods provided more simple, reliable research methods for system development, population genetic structure and quality control, and other fields. However, the application of domestic experimental rabbits is restricted because of their unstalbe quality and unclear genetic background. In this paper, applications of the technology of molecular markers on the analysis of genetic diversity of rabbits are summarized, aimed at providing some help to genetic testing of experimental rabbits.
出处
《中国比较医学杂志》
CAS
2012年第9期72-76,共5页
Chinese Journal of Comparative Medicine
基金
重大疾病动物模型和实验动物资源的标准化及评价体系的建立(2011BAI15B00)
关键词
实验兔
分子遗传标记
遗传多样性
遗传检测
Experimental rabbits
Molecular genetic markers
Genetic diversity
Genetic detecting
