摘要
目的探讨复方甘草酸苷联合咪唑斯汀治疗荨麻疹的临床疗效。方法抽取在本院门诊治疗荨麻疹的188例患者,随机分为两组,每组各94例,对照组服用咪唑斯汀治疗,观察组采用咪唑斯汀联合复方甘草酸苷片服用,观察两组的疗效及有无不良反应。结果治疗后两组患者的症状总积分均下降,且对照组的症状总积分高于观察组,差异有统计学意义(P<0.05)。对照组的有效率为59.57%,观察组的有效率为86.17%,两组间治疗率的比较,差异有统计学意义(P<0.05),观察组的有效率明显高于对照组。除此之外,两组间不良反应发生率差异无统计学意义(P>0.05)。结论联合复方甘草酸苷和咪唑斯汀治疗慢性荨麻疹疗效显著,优于单一应用咪唑斯汀治疗,具有较高的临床价值。
Objective To discuss the clinical efficacy of compound glycyrrhizin combined with mizolastine in the treatment of urticaria. Methods One hundred and eighty-eight patients with urticaria were extracted and divided randomly into two groups with each group 94 cases in our hospital. The control group （94 cases） was treated with mizolastine, while the observation group （94 cases） was treated with mizolastine combined with compound glycyrrhizin. The efficacy and adverse reaction were observed during the course of treatment. Results The total symptom scores of both groups decreased after the treatment and showed that the difference was statistical significance （P 〈 0.05）, with the total symptom score of control group was higher than that of observation group. The efficiency rate of control group was 59.57%, while the efficiency rate of observation group was 86.17%, There was a significant statistical difference between the rate of therapy in two groups （P 〈 0.05）, with the efficiency rate of observation group was higher than that of control group. In addition, the incidence of adverse reaction of both groups had no statistics significance （P 〉 0.05）. Conclusion Compound glycyrrhizin combined with mizolastine is effective and safe in treating urticaria, which is better than single application of mizolastine and has higher clinical value.
出处
《中国当代医药》
2012年第28期71-72,共2页
China Modern Medicine
关键词
复方甘草酸苷联合咪唑斯汀
荨麻疹
临床疗效观察
不良反应
Compound glycyrrhizin combined with mizolastine
Urticaria
Observation on clinical efficacy
Adverse reaction
