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恶性脑胶质瘤手术联合放疗预后及相关因素分析 被引量:4

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摘要 目的探讨恶性脑胶质瘤手术联合放疗的临床疗效及预后影响因素。方法外科手术后经病理证实的39例恶性脑胶质瘤患者给予放疗。Log-rank进行单因素分析,Cox回归多因素分析。结果本组中位生存时间15个月,1、3、5年生存率分别为64.4%、28.8%、17.7%。单因素分析显示影响预后的因素包括:年龄、Karnofsky评分、病理分级、手术切除程度、手术至放疗时间。多因素分析显示年龄、Karnofsky评分、病理分级、手术切除程度是影响预后的独立因素。结论外科医师应在不影响患者功能的前提下尽可能完整切除恶性脑胶质瘤,缩短手术至放疗时间以改善预后。
作者 是旌 王峰
出处 《军医进修学院学报》 CAS 2012年第10期1067-1068,共2页 Academic Journal of Pla Postgraduate Medical School
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