摘要
本文检测了43例肺癌患者血浆纤维结合蛋白(Plasma fibronectin PFN)值。肺癌患者(除小细胞未分化癌)PFN 值明显高于正常人及肺部良性肿物患者,有非常显著的统计学意义(P<0.01)。当肺癌合并肺炎时PFN 不升高,而且随肺癌临床病理分期进展,PFN 均值呈下降趋势。本文结果认为,PFN 对于肺癌的辅助诊断具有一定应用价值。
Plasma fibronectin(PFN)of 43 ca-ses of lung cancer were examined.The mean value of PFN in lungcancer group was(39.30mg/dl)higherthan that in normal(31.80mg/dl)andbenign pulmonary masses grous(27.20mg/dl),except of small celllung cancer,the difference was of re-markablysignificante(P<0.01).Howe-ver,the value of PFN was not elev-ated,or even declined in patients oflung cancer complicated by long-termrepeated intrapulmonary infection orchronic obstructive pulmonary disea-ses.The mean value of PFN had adeclining tendency as progession ofclinical pathological staging of lungcancer.The authors indicated considerthat the determning PFN had certainvaluein to early diagnosis and deffer-etial diagnosis of primary lung cancer.
