摘要
本文观察了15例慢性粒细胞白血病患者和5例慢粒急变患者血浆vWf和Fn的含量变化,结果发现,慢粒患者血浆vWf显著升高,Fn下降,慢粒急变者vWf升高更为显著,Fn也显著地降低,两者从不同侧面反映了慢粒及其急变者的病理生理变化,似提示与预后有关。
The plasma level of von Willebrand factor(vWf) and fibronectin(Fn) in 15 cases of chronic myeloid leukemia(CML) and 5 cases of acute transfcrmation was studied. The increase of vWf and the decrease of Fn was found significantly in CML, especially in acute transformation cases,Thus, the plasma von Willebrand Factor and Fibronectin determinatin may be used as the parameter for the severity in CML, especially for acute transformation.
关键词
VWF
纤维结合蛋白
粒细胞白血病
von Willebrand factor(vWf)
fibronectin(Fn)
chronic myeloid leukemia (CML)
vcute transformation
