期刊文献+

高场非对称波形离子迁移率谱的正弦切割波形产生与离子分离特性 被引量:2

Generation and Ion Separation Behavior of Clipped-Sinusoidal Waveform for High-Field Asymmetric Waveform Ion Mobility Spectrometry
在线阅读 下载PDF
导出
摘要 高场非对称波形离子迁移率谱(FAIMS)是一种利用不对称电场进行气相离子分离和检测的新技术。本文使用一种基于单电感反激电路产生正弦切割波形的方法,实现FAIMS的非对称分离电场,分析了该正弦切割波形在在0.8 MHz~1.4MHz频率范围的波形变化规律;使用10.6 eV(λ=116.5 nm)紫外灯为离化源的平板型FAIMS器件,研究在正弦切割波作用下的离子分离效果。结果表明,所产生的正弦切割波的正弦部分不随频率变化,当频率变化到1 MHz(即正弦部分与整个周期比值到达0.42)时,离子分离效果和检测分辨率最优。 High-Field asymmetric waveform ion mobility spectrometry(FAIMS)is a new technology for separation and identification of gas-phase ions.A low cost generator of clipped-sinusoidal waveform is constructed based on a simplified flyback circuit.The profile of clipped-sinusoidal waveforms under 0.8 MHz^1.4 MHz was analyzed and the properties of ion separation were tested with acetone,cyclohexane,and ethanol using a planar FAIMS with a 10.6 eV(λ= 116.5 nm)UV lamp as photoionization source.The results show that the best resolution can be obtained at a frequency of 1 MHz(ratio of sinusoidal part to whole waveform is equal to 0.42)and the resolution increases with the amplitude of clipped-sinusoidal waveform.
出处 《传感技术学报》 CAS CSCD 北大核心 2012年第7期926-929,共4页 Chinese Journal of Sensors and Actuators
基金 国家自然科学基金项目(60901048)
关键词 高场非对称波形离子迁移率谱 不对称波形 紫外光致离化 反激电路 FAIMS asymmetric waveform photoionization flyback circuit
  • 相关文献

参考文献12

  • 1Kolakowski B M, Mester Z. Review of Applications of High-Field Asymmetric Waveform Ion Mobility Spectrometry ( FAIMS ) and Differential Mobility Spectrometry(DMS) [ J]. Analyst,2007,132 : 842-864.
  • 2Shvartsburg A A, Tang K Q, Smith R D. Differential Ion Mobility Separations of Peptides with Resolving Power Exceeding 50 [ J ]. Analytical Chemistry ,2010,82:32-35.
  • 3Shvartsburg A A, Smith R D. Optimum Waveforms for Differential Ion Mobility Spectrometry (FAIMS) [ J ]. Journal of the American Society for Mass Spectrometry,2008,19 : 1256-1295.
  • 4Papanastasiou D, Wollnik H, Rico G, et al. Differential Mobility Separation of Ions Using a Rectangular Asymmetric Waveform[ J ]. Journal of Physical Chemistry A ,2008,112:3638-3645.
  • 5Krylov E V, Coy S L, Vandermey J, et al. Selection and Generation of Waveforms for Differential Mobility Spectrometry [ J ]. Rev Sci Instrum,2010,81:24101.
  • 6Krylov E V,Pulses of Special Shapes Formed on a Capacitive Load [ J ]. Instruments and Experimental Techniques, 1997 ,40 :628-631.
  • 7Arce L, Menendez M, Garrido-Delgado R, et al. Sample-Introduction Systems Coupled to Ion-Mobility Spectrometry Equipment for Determining Compounds Present in Gaseous, Liquid and Solid Samples[J].Trac-Trends in Analytical Chemistry ,2008 ,27 :139-150.
  • 8王乐,王镝,於锦,王平,胡燕婕,应可净.基于谐振型SAW传感器的呼吸检测系统设计[J].传感技术学报,2011,24(4):498-502. 被引量:11
  • 9郭希山,童基均,陈裕泉,杨祥龙.用于室内有毒气体快速检测的便携式CC/SAW电子鼻[J].传感技术学报,2006,19(1):68-73. 被引量:8
  • 10Krylov E V, Nazarov E G, Miller R A. Differential Mobility Spectrometer : Model of Operation [ J ]. International Journal of Mass Spectrometry, 2007,266 : 76- 85.

二级参考文献32

  • 1应可净,黄强.呼吸气体检测在肺癌早期诊断中的应用[J].国际呼吸杂志,2006,26(2):143-145. 被引量:7
  • 2张靖,周渭.频标比对新方法的实现方案研究[J].电子质量,2006(11):8-12. 被引量:2
  • 3Turner A P F, Magan N. Electronic Noses and Disease Diagnostics[ J ]. Nature Reviews Microbiology,2004,2 : 161 - 166.
  • 4Zhang Qintao, Wang Ping, Li Jianping, et al. Diagnosis of Diabetes by Imaging Detection of Breath Using Gas-Sensitive LAPS[ J]. Biosensors & Bioelectronies ,2000,15 (5-6) :249-256.
  • 5Phillips M, Gleenon K, Hughes J M B, et al. Volatile Organic Compounds in Breath as Markers of Lung Cancer: a Cross-Sectional Study [ J ]. Lancet, 1999,353 : 1930-1933.
  • 6Pauling L, Robinson A B,Teranishi R, et al. Quantitative Analysis of Urine Vapor and Breath by Gas-Liquid Partition Chromatography. Proc Nat Acad Sci USA,1971,68(10) :2374-2376.
  • 7Watson G, Horton W, Staples E. SAW Resonators as Vapor Sensor [C]//IEEE 1990 Ultrasonics Symposium Proceedings: vol 1. IEEE. 1990.311-314.
  • 8Watson G, Horton W, Staples E. Gas Chromatography UtilizingSAW Sensors [ C]//IEEE 1991 Ultrasonics Symposium: vol 1. IEEE, 1991. 305-309.
  • 9Chen X, Xu F J, Wang Y, et al. Study of the Volatile Organic Compounds Exhaled by Lung Cancer Cells in Vitro for Breath Diagnosis [J]. CANCER ,2007,110(4 ) : 835-844.
  • 10Staples E J, Watson G W, Horton W J. Temperature Programmed Desorption Characteristics of SAW Resonators [ C ]//IEEE 1991 Ultrasonics Symposium : vol 1. IEEE 1991. 317-320.

共引文献17

同被引文献7

引证文献2

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部