摘要
目的:探讨灯盏细辛注射液所致不良反应的一般规律及特点,指导临床合理用药。方法:通过检索1979—2012年国内公开发表的医学期刊报道应用灯盏细辛注射液致不良反应案例,并进行文献计量学分析。结果:共检索到灯盏细辛注射液不良反应个案报道15篇涉及25例,其不良反应与性别、年龄、溶媒、剂量、联合用药有相关性,临床主要表现为过敏反应,严重者可出现过敏性休克及多器官功能损害。结论:临床医师及药师应了解灯盏细辛注射液所致不良反应的规律和特点,规范合理用药,加强应用监测,减少不良反应的发生。
Objective： To investigate the effect of Dengzhanxixin injection induced adverse reactions of the general rule and characteristic, guide clinical rational drug use. Method： Through the retrieval of 1979-2012 reported in domestic medical journals of Dengzhanxixin injection induced adverse reactions and case, literature metrology analysis analysis. Result： The search to Dengzhanxixin injection in 25 cases of adverse drug reactions, the adverse reactions closely related with gender, age, solvent, dose, the combination drugs. The main clinical manifestations of allergic reactions, severe cases can cause allergic shock and multiple organ dysfunction. Conclusion： Clinicians and pharmacists should understand of Dengzhanxixin injection pattern and characteristics of adverse reactions, rational drug use norms, strengthen the application of monitoring, reduce the occurrence of adverse reactions.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2012年第18期2789-2791,共3页
China Journal of Chinese Materia Medica
基金
国家"重大新药创制"科技重大专项(2009ZX09502-030)"中药上市后评价关键技术研究"
关键词
灯盏细辛注射液
不良反应
文献分析
Dengzhanxixin .injection
adverse reaction
literature analysis
