不同年龄CINII-III患者LEEP术前后人乳头瘤病毒的随访的临床观察被引量：1

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摘要目的检测不同年龄组患者宫颈上皮内瘤变II—III级高频电刀锥切术（LEEP）治疗后高危人乳头瘤病毒（HPV）及亚型清除情况，评价手术疗效及随访价值。方法随机抽取75例因CINII—III接受LEEP手术并按医嘱行术后随访的患者，按年龄分为2组，术前均行TCT（液基细胞）及HPV队乳头瘤病毒片佥测，并证实高危型HPV感染。治疗后6月复查TCT及HPV，如有TCT异常或HPV持续感染再次行活检病理学检查。比较HPV术后清除及HPV亚型持续感染率。结果2个年龄组的患者LEEP手术后HPV清除率分别为947％（32／34），63．4％（26／41），2组之间治疗后HPV清除率有显著差异（P〈0．05）。术后6个月41～50岁年龄组HPV16亚型持续感染率与28-40岁组相比差异有统计学意义（P〈0．05）。结论LEEP是一种简单安全的手术。可在切除病变的同时清除HPV。术后6个月HPV分型检测是一种很好的随访方式。对年龄较大者持续感染HPV应密切长时间的随访。

作者周丽

机构地区上海市奉贤区中医医院

出处《医学信息》 2012年第8期174-175,共2页 Journal of Medical Information

关键词宫颈上皮内瘤变人乳头瘤病毒高频电刀锥切术

分类号 R737.33 [医药卫生—肿瘤]

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