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衰老研究的新纪元 被引量:25

A New Epoch of Aging Study
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摘要 在人类历史进入 2 1世纪的时刻 ,生命科学关于衰老原理的研究迎来了一个划时代的新纪元 .多领域、多层次、跨学科的衰老研究 ,在分子水平上将遗传基因衰老学说、自由基氧化衰老学说、糖基化衰老学说和交联衰老学说汇聚到了一个新的焦点羰基毒化衰老学说 .由于现代生命科学逐步认识到了羰 -氨反应是诸多生物副反应中的一个核心过程 ,该反应引起了衰老机理研究的极大重视 . At the dawn of the 21st century, studies of biochemical mechanisms of aging also come on to a remarkable new epoch. The multidisciplinary nature of aging studies, including molecular mechanisms of the programmed gene theory of aging, the free radical/oxidative stress theory of aging, the glycation/Maillard reaction theory of aging, the cross linking theory of aging eventually seem to highlight a primary and central cause of aging, the carbonyl toxification cause of aging, which is attracting much attention in the field related.
作者 印大中
出处 《生命科学研究》 CAS CSCD 2000年第2期95-101,共7页 Life Science Research
基金 教育部留学回国人员基金项目 湖南省教委科研基金
关键词 衰老原理 自由基 氧化 粮基化 羰基毒化 aging free radicals oxidative stress glycation carbonyl stress
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