期刊文献+

《放射性神经系统疾病诊断标准》解读 被引量:1

Explanation of Diagnostic Criteria for Radiation.Induced Nervous System Disease
原文传递
导出
摘要 国家职业卫生标准——(傲射性神经系统疾病诊断标准》已经由卫生部发布并实施。此标准原为放射性脑、脊髓、外周神经损伤3个独立的标准,但在临床工作中3者的损伤往往相伴出现,为了实现标准的整体性及可操作性,因此将3个诊断标准合并为(傲射性神经系统疾病诊断标准》,此标准是在广泛调研国内外相关文献、总结临床实践经验,并参考国外相关出版物的基础上制定的。此标准主要适用于职业性放射性神经系统疾病的诊疗,医疗照射引起的神经系统疾病的诊疗也可参照使用。为了更好地执行此标准,也为了能正确处理放射性神经系统损伤,该文对标准的主要内容包括剂量阈值、临床表现、分度标准、治疗原则等进行解读。 National occupational health standard--Diagnostic Criteria for Radiation-Induced Ner-vous System Disease has been issued and implemented by the Ministry of health. This standard contained three independent criteria of the brain, spinal cord and peripheral nerve injury. These three kinds of disease often go together in clinic, therefore, the three diagnostic criteria were merged into radioactive nervous system disease diagnostic criteria for entirety and maneuverability of the standard. This standard was formulated based on collection of the clinical practice experience, extensive research of relevant literature and foreign relevant publications. It is mainly applied to diagnosis and treatment of occupational radiation-induced ner- vous system diseases, and to nervous system diseases caused by medical radiation exposure as well. In order to properly implement this standard, also to correctly deal with radioactive nervous system injury, the main contents of this standard including dose threshold, clinical manifestation, indexing standard and treatment principle were interpreted in this article.
出处 《国际放射医学核医学杂志》 2012年第4期221-226,共6页 International Journal of Radiation Medicine and Nuclear Medicine
基金 基金项目:卫生部行业基金(201002009),卫生部标准研究课题(2001-09-05,2006-09-02,2006-09-04)
关键词 神经系统疾病 放射疗法 职业卫生标准 Nervous system diseases Radiotheraphy Occupational health criteria
  • 相关文献

参考文献30

  • 1InternationalCommissiononRadiologicalProtection.电离辐射的非随机效应(国际辐射防护委员会4l号出版物).程违,李元敏,李树德,译.北京:原子能出版社,1988:40-41.
  • 2张秀萍,黄赖机,李健,梁颖.鼻咽癌放射治疗与放射性脑损伤[J].重庆医学,2002,31(7):611-612. 被引量:5
  • 3Lee AW, Foo W, Chappell R, et al. Effect of time, dose, and fractionation on temporal lobe necrosis following radiotherapy for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys, 1998, 40 ( 1 ): 35-42.
  • 4Parsons JT, Bova FJ, Fitzgerald CR, et al. Radiation optic neuropathy after megavoltage external-beam irradiation: analysis of time-dose factors. Int J Radiat Oncol Biol Phys, 1994, 30(4):755-763.
  • 5刘雅洁,蔡伟明,徐国镇.鼻咽癌放疗后放射性脑损伤分析[J].中华放射医学与防护杂志,2001,21(5):359-360. 被引量:12
  • 6冯勤付,杨宗贻,汪楣,殷蔚伯.放射性脊髓炎的潜伏期与预后分析[J].中华放射医学与防护杂志,2003,23(2):104-105. 被引量:9
  • 7丁学华,朱诚,张光霁,张晓鹏,熊海健,王全林.后装高剂量率^(192)Ir近距离放射治疗脑深部胶质瘤21例初步报告[J].功能性和立体定向神经外科杂志,1993,6(1):4-5. 被引量:3
  • 8Pavy JJ, Denekamp J, Letschert J, et al. EORTC Late Effects Working Group. Late Effects toxicity scoring: the SOMA scale. Int J Radiat Oncol Biol Phys, 1995, 31(5): 1043-1047.
  • 9National Cancer Institute. Common terminology criteria for adverse events v3.0 (CTCAE). Bethesda(MD): NCI, 2006.
  • 10崔念基,卢泰祥,邓小武,等.实用临床放射肿瘤学.上海:中山大学出版社,2005:738.

二级参考文献51

共引文献56

同被引文献17

  • 1章龙珍,曹远东,陈勇,于常州,庄明.全脑常规分割外照射对大鼠血脑屏障药物通透性的影响[J].中华放射肿瘤学杂志,2006,15(3):229-232. 被引量:17
  • 2Li YQ, Chen P, Haimovitz-Friedman A, et al. Endothelial apoptosis initiates acute blood-brain barrier disruption after ionizing radiation [ J ]. Cancer Res, 2003, 63 (18) :5950-5956.
  • 3Yuan H, Gaber MW, Boyd K, et al. Effects of fractionated radiation on the brain vasculature in a murine model:blood-brain barrier permeability, astrocyte proliferation, and ultrastructural changes [Jl. Int J Radiat Oncol Biol Phys, 2006, 66 (3):860- 866. DOI : 10. lO16/j, ijrobp. 2006.06. 043.
  • 4Nakamura K, Tan F, Li ZJ, et al. NGF activation of TrkA induces vascular endothelial growth factor expression via induction of hypoxia-inducible factor-lct[ J]. Mol Cell Neurusci, 2011, 46 (2) :498-506. DO1:10. 1016/j. mcn. 2010.12. 002.
  • 5Morris R. Developments of a water-maze procedure for studying spatial learning in the rat [J~. J Neurosci Methods, 1984, 11 ( 1 ) :47-60. DOI : 10.1016/0165-0270 ( 84 ) 90007-4.
  • 6Warrington JP, Ashpole N, Csiszar A, et al. Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications [J]. J Vasc Res, 2013, 50(6) :445-457. DOI:10. 1159/000354227.
  • 7Fisher M. Pericyte signaling in the neurovascular unit [ J ]. Stroke, 2009, 40 ( 3 ) : S13-S15. DOI : 10. 1161/STROKEAHA. 108.533117.
  • 8Achanta P, Fuss M, Martinez JL Jr. Ionizing radiation impairs the formation of trace fear memories and reduces hippocampal neurogenesis [Jl. Behav Neurosci, 2009, 123 (5) :1036-1045. DOI : 10. 1037/a0016870.
  • 9Raber J, Rola R, LeFevour A, et al. Radiation-induced cognitive impairments are associated with changes in indicators of hippocampal neurogenesis [ J]. Radiat Res, 2004, 162 ( 1 ) :39- 47. DOI:10. 1667/rr3206.
  • 10Rola R, Raber J, Rizk A, et al. Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice [J]. Exp Neurol, 2004, 188 (2) :316-330. DOI: 10. 1016/j. expneurol. 2004.05. 005.

引证文献1

二级引证文献18

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部