摘要
测定了胃阴虚证患者的胰腺外分泌功能(BT-PABA 试验),观察了非胃部疾病胃阴虚证病例胃粘膜光镜和电镜下组织形态学变化。结果发现,胃阴虚患者胰腺外分泌功能低下;胃粘膜有不同程度的形态学损伤。光镜下显示轻度变性,或呈慢性胃炎;电镜下显示胃粘膜细胞的线粒体、粗面内质网损伤,壁细咆、主细胞和 G 细胞变性改变。
Exocrine function of pancreas(BT-PABA test)in 13 patients with SYDS was examined and gastric membrane in 5 cases with SYDS other than gastric diseases was observed under light-and electro-microscopy.Theresults were as follows:urine rate of recovery of PABA in SYDS was 35. 42±14.33% and that in the control with same age was 64.70±10.55%.The rate in SYDS was decreased obviously(P<0.001).Under light microscopy gastric,mucosa of patients with SYDS showed slight gland degenerative atrophy,smaller cytoplasm,,eosinophilic decrease of parietal cells and infiltration of inflammatory cells in interstitial tissue.Under electro-microscopy,the main changes of the gastric mucosa with SYDS were severe mitochondria damage,inflating rough endoplasmic pools and large vacuole at which membrane major particles of ribosomes disappeared, degenerated secretory vessels and formation of myelinfigure in parietal cells,decrease of secretory particles in main cells,degeneration in some degree,and decrease of nervous secretory particles in G.cells and damaged interstitial capillaries.The results in this study suggested that the exocrine function of pancreas in patients with SYDS after abdominal operation or with severe acute abdomi- nal diseases was decreased and there were some damages in energy supply and protein manufactur- ing.systems of the gastric mucosa and functional disturbances of main cells,parietal cells and G cells in patients.with SYDS.
