摘要
分析经口染毒乙醇 35天的雄性小鼠的精子数量、活动度、精子畸形率及睾丸细胞染色体畸变 ,研究乙醇对雄性小鼠精子生成的影响。结果表明 ,40 0 0mg/kg组和 45 0 0mg/kg 组小鼠精子活动度明显下降 ;30 0 0 ,40 0 0和 45 0 0mg/kg 组精子畸形率明显增高 ;45 0 0mg/kg 组睾丸细胞染色体畸变率明显增高 ,与阴性对照组相比 ,上述指标差异均有显著性 (P <0 0 1)。
After gavaged with ethanol for 35 days,the number,motility and deformity of sperm and chromosome aberration in testicle cells of male mice were determined.The results showed that in 4 000 mg/kg group the sperm motility decreased,in 3 000 mg/kg and 4 000 mg/kg groups the rate of sperm deformity increased,and in 4 500 mg/kg group the rate of chromosome aberration in testicle cells increased.It indicated that ethanol could damage spermatogenesis in mice.
出处
《工业卫生与职业病》
CAS
CSCD
2000年第4期209-212,共4页
Industrial Health and Occupational Diseases
关键词
乙醇
精子生成
睾丸细胞
染色体畸变
Ethanol Spermatogenesis Testicle cell Chromosome aberration
