摘要
目的探讨原发性干燥综合征(pSS)患者发病特点及预后。方法选择2008年9月至2011年9月门诊及住院的原发性干燥综合征患者33例的病历资料进行回顾性分析。结果原发性干燥综合征住院人数呈上升趋势,发病高峰年龄为31～54岁;男女性别比为1∶27.3;首诊症状中最多见的是口干、眼干和关节痛:抗SSA、SSB抗体的阳性率分别为89.4%和47.6%:唇腺病理检查者12例,3～4级占50.6%。并发症中最多见的为肾小管酸中毒(19.6%)。结论 pSS近年来就诊人数呈上升趋势;唇腺病理和抗SSA、SSB抗体对pSS的诊断有重要意义;pSS尚不能根治,并发症的处理仍是本病治疗的关键。
Objective To explore the primary Sjogren syndrome （pSS） patients clinical features and prognosis. Methods In 2008 september -2011 september outpatients and inpatients of primary Sjogren syndrome： a report of 33 cases of clinical data were retrospectively analyzed. Results Primary Sjogren syndrome hospitalization number shows ascendant trend, the peak age of onset for31to 54 years of age; sex ratio is 1∶ 27.3; the first symptom in most of the dry mouth, dry eye and joint pain： Anti SSA, SSB antibody positive rates were 89.4% and47.6%： the labial gland pathology examination in 12 cases,3to 4 grade50.6%. The most common complications of renal tubular acidosis （19.6%）. Conclusion PSS in recent years the number of hospitalizations upward trend; labial gland pathology and resistance to SSA, SSB antibodies to pSS diagnosis has important significance; pSS is not curative, treatment of complications in the treatment of this disease is still the key.
出处
《中国实用医药》
2012年第19期60-61,共2页
China Practical Medicine
关键词
干燥综合征
并发症
临床分析
Sjogren syndrome； Complication； Clinical analysis
