摘要
目的 :考察表面活性剂提高超临界流体萃取 (SFE)效率的作用。 方法 :以麻黄碱为研究对象 ,用含 5 %苯基硅氧烷交联毛细管柱进行分析 ,考察琥珀酸二辛酯磺酸钠 (DSS)、十二烷基硫酸钠 (SDS)、1-庚烷基磺酸钠 (SHS)和羧甲基纤维素钠(CMC- Na) 4种表面活性剂对超临界流体溶解性的影响。 结果 :发现 DSS,SDS,SHS及 CMC- Na分别能够提高萃取效率2 46 .8% ,12 3.4% ,83.0 %和 5 3.2 % ,前 3者与 CMC- Na比较均具有非常显著性差异 (P<0 .0 1)。这与这些表面活性剂的分子结构有关 ,分子的脂溶性部分越大 ,其对 SFE萃取效率提高越多 ,DSS对超临界二氧化碳的增溶作用最强 ,提高萃取效率明显。 结论 :表面活性剂能显著提高 SFE效率 ,为生物碱类化合物的
Objective: To observe the effect of surfactant in enhancing the efficiency of supercritical fluid extraction (SFE). Methods: Dioctyl sodium sulfosuccinate (DSS), sodium dodecyl sulfate (SDS), 1 heptanesulfonate (SHS), CMC Na were used as the surfactants, their influences on extraction of ephedrine by SFE were studied by 5% phenyl cross silicon capillary gas chromatography (CGC). Results: DSS, SDS, SHS and CMC Na enhanced the efficiency of SFE by 246.8%, 123.4%, 83.0% and 53.2% respectively, which was due to their molecular structure, the more liposoluble parts they have, the higher the efficiency. DSS had the best effect of solubilization among these surfactants. Conclusion: This method can obviously increase the solubilization of supercritical CO 2. It offers a valuable way for SFE of alkaloid.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2000年第5期463-465,共3页
Academic Journal of Second Military Medical University
基金
国家自然科学基金资助项目!(39770904)
