摘要
相对于传统医用金属材料,镁及其合金具有低密度、高比强度和比刚度以及与人体密质骨相近的弹性模量。这类新型医用金属材料的应用使人们摒弃了通常将医用金属作为生物惰性材料使用的传统思想,而巧妙地利用镁及其合金在人体环境中可发生腐蚀(降解)的特性,以可控方式实现其植入物在体内的修复功能,并逐渐降解直至最终消失。本文综述了目前文献报道的各种可降解镁合金医疗器械及其相关在体试验结果,指出其优势与不足,并对其未来发展前景进行了展望。
Compared to traditional biomedical metallic materials,magnesium and its alloy possess low density,high specific strength and stiffness,and elastic modulus closed to natural bone.Instead of using metallic biomaterials as bio-inert materials,magnesium alloy medical devices play functional roles in vivo and then degradate gradually until completely disappear based on their biocorrosion/ biodegradability.The present paper reviews all kinds of magnesium alloy medical devices reported in literatures and their related experimental results in vivo.The advantages and main drawbacks of these magnesium medical devices are summarized.Finally,the prospects of using magnesium alloy medical devices for future clinical applications were proposed.
出处
《中国医疗器械信息》
2012年第7期9-13,28,共6页
China Medical Device Information
基金
国家973计划(2012CB619102)
国家863计划主题项目(2011AA030101
2011AA030103)
国家自然科学基金(31170909)资助
关键词
镁及镁合金
医疗器械
可降解金属
研发现状
Mg and Mg alloy； medical devices； biodegradable metals； research ＆ development status
