摘要
报告测定四组不同烧伤面积病人血清中四种载体蛋白及补体(C_3)的含量,并分析与不同烧伤面积、感染、败血症及死亡的关系。伤后早期前白蛋白、转铁蛋白、铜兰蛋白以及C_3四组间下降幅度有很大差异,4周时三、四组转铁蛋白、前白蛋白还持续处于低水平,铜兰蛋白和C_3继而升高。触珠蛋白伤后升高,4周时一、二组开始下降,三、四组仍维持较高水平。结果表明:载体蛋白和C_3的变化与烧伤面积、感染、死亡有密切的关系,观察有助于病情判断和预后分析。
Four bearer-proteins iacluding prealbumin (Pal). ceruloplasmin (CP). transferrin (Tf) and haptoglobin (HP) and C3 were determined in patients following burn injury .The patients were divided into 4 groups according to the TBSA, i.e. group I (1～10%), group 2(11～ 30%), group 3 (31～60%) and group 4 (61～98%). Early after burn injury Pal. CP, Tf and C3 decreased markedly but C3 and CP were followed by a elevation slightly higher than normal control in group 1 and 2 but not in group 3 and 4, while Tf and Pal kept in lo- wer level till 4 weeks after burn injury. Only elevated HP after burn injury was noticed and then decreased in group 1 and 2.
