摘要
目的探讨血清学指标联合颈部透明膜产前筛查21-三体综合征的临床价值。方法选取2008年1月—2011年12月采用羊水细胞染色体核型确诊的21例21-三体综合征为观察组,选取同期的21例健康孕妇为对照组,将两组孕妇的血清β-hCG、AFP、FE3及胎儿颈部透明膜厚度进行比较。结果观察组血清β-hCG及胎儿颈部透明膜厚度均大于对照组,而AFP、FE3则低于对照组,两组比较差异有统计学意义(P<0.05)。结论血清学指标联合颈部透明膜产前筛查21-三体综合征的临床价值较高。
Objective To study the clinical value of serum index combined with neck transparent film in the prenatal screening for 21-Trisomy syndrome. Methods 21 patients diagnosed by karyotype of amniotic fluid cell,; from January 2008 to December 2011 were selected as observation group, 21 healthy pregnant women at the same time were selected as control group, then the serumβ-hCG, AFP, FE3 and thickness of fetus neck transparent film of two groups were compared. Results The se- rum β-hCG and thickness of fetus neck transparent film of observation group were both bigger than those （ff control group, AFP and FE3 were both lower than those of control group, all P 〈 0. 05, there were all significant differences. Conclusion The clinical value of serum index combined with neck transparent film in the prenatal screening for 21-Trisom~ syndrome is higher.
出处
《广州医药》
2012年第4期31-33,共3页
Guangzhou Medical Journal
