摘要
目的:观察顽固性便秘病人的营养状况,评估金陵术对病人营养状况和水电解质平衡的影响。方法:选择接受金陵术式治疗的98例顽固性混合型便秘病人,测定术前和术后1、3、6和12个月的机体组成及血清清蛋白、转铁蛋白、前清蛋白、纤维连接蛋白、钾、钠、氯、磷、镁、钙等水平,评估金陵术对病人营养状况和水电解质平衡的影响。并采用胃肠生活质量评分、Wexner便秘评分、术后腹泻率和腹泻程度分级,评价金陵术式治疗顽固性混合型便秘的临床结果。结果:金陵术可显著改善病人的便秘症状,提高生活质量,但术后早期会出现排便频次增多和不同程度腹泻,少数病人出现电解质失衡。病人术后1个月营养指标显著下降,术后3个月逐渐恢复,术后6个月、12个月可恢复至术前水平。结论:金陵术治疗顽固性混合型便秘,能改善病人生活质量,对机体长期营养状况和水电解质平衡无明显影响。
Objective： To investigate the nutritional status and homeostasis of refractory constipation patients pre-and post-Jinling＇s procedure over a 12 months follow up.Methods： 98 refractory constipation patients recieved Jinling procedure were enrolled in the study.The Gastrointestinal Quality of Life Index（GIQLI）,Wexner＇s constipation scorces,stool frequency,body composition and serum albumin,transferrin,prealbumin,fibronectin and major electrolytes were recorded and analyzed with paired-sample t test.Results： Nutritional status of the refractory constipation patients were normal.With the effective improvement on functional outcome,frequently stool and diarrhea were profound during the early stage after Jinling＇s procedure.Compared with preoperative nutritional status,nutrition at 1 month follow up showed significant decrease in all parameters and improved at 3 month.No significant difference were found at both 6 month and 12 month follow up compared with preoperative baseline.Electrolyte disturbances were found in few patients without clinical symptoms.Conclusion： Jinling procedure is an effective procedure on refractory constipation.Although subtotal colectomy is performed,Jinling＇s procedure doesn＇t jeopardize the nutritional status and electrolyte balance of constipation patients.
出处
《肠外与肠内营养》
CAS
北大核心
2012年第4期210-213,共4页
Parenteral & Enteral Nutrition
关键词
顽固性便秘
外科治疗
营养状况评估
Refractory constipation
Surgical treatment
Nutrition status
