摘要
目的:了解妊娠期高血压疾病(HDCP)患者的肾功能各项指标出现的变化及其在HDCP诊断治疗过程中的临床意义。方法:对146例HDCP患者(实验组)肾功能的多项指标进行检测,并用同期体检健康的孕产妇120例(对照组)作对照,分别检测两组的血清肌酐(Cr)、尿素氮(BUN)与尿酸(UA)水平。结果:实验组的Cr、BUN、UA水平均比对照组高,且比较均有显著性差异(P<0.05或P<0.01)。实验组和对照组的Cr水平的频数分布比较无显著性差异(P>0.05);而血清BUN与UA水平的频数分布比较有显著性差异(P<0.05或P<0.01)。不同程度HDCP患者之间Cr、BUN、UA水平的比较均有显著性差异(P<0.05或P<0.01)。结论:HDCP患者有不同程度的肾功能损害,表现为Cr、BUN、UA水平的升高,病情越重肾功能损害越显著,因此临床中应重视对HDCP患者肾功能的测定。
Objective：To find out the changes of renal function in patients with hypertensive disorders complicating pregnancy（HDCP） and its clinical significance in the diagnosis and treatment of HDCP.Methods：The renal function of 146 HDCP patients（experimental group） was detected,and 120 cases of physical health maternal at the same period were taken as control group.The levels of serum creatinine（Cr）,urea nitrogen（BUN） and uric acid（UA） were detected respectively.Results：The levels of Cr,BUN,UA in experimental group were higher than the control group and were significantly difference（P〈0.05 or P〈0.01）.The frequency distribution of Cr level in experimental group and control group were not significantly difference（P〉0.05）;and the frequency distribution of serum BUN level and UA level were significantly difference（P〈0.05 or P〈0.01）.The levels of Cr,BUN,UA in the patients with different degrees of HDCP were significantly difference（P〈0.05 or P〈0.01）.Conclusion：HDCP patients have renal dysfunction at different degree,it manifesteds as the increase of levels of Cr,BUN,UA,the more severe the disease is,the more significant renal function damage.Therefore more attention should be paid to the clinical determination of renal function in patients with HDCP.
出处
《中国妇幼保健》
CAS
北大核心
2012年第20期3111-3113,共3页
Maternal and Child Health Care of China
关键词
妊娠期高血压疾病
肾功能
肌酐
尿素氮
尿酸
Hypertensive disorder complicating pregnancy（HDCP）
Renal function
Creatinine
Urea nitrogen
Uric acid
