摘要
以四甘醇 (C8H18O5)、氯甲烷 (CH3Cl)及固体碱性氢氧化物 (MOH)为原料 ,按n (C8H18O5)∶n (CH3Cl)∶n (MOH) =1∶( 2～ 3)∶( 2～ 5) ,采用Williamson法合成四甘醇双甲醚。反应温度为55～ 90℃ ,反应压力 0 6MPa ,反应时间为 3h ,四甘醇转化率大于 99% ,双醚选择性为 78 6%。同时以四甘醇的副产四、五甘醇混合物为原料合成四、五甘醇双甲醚混合物 ,反应只需约 2h即可完成 ,双醚选择性为 93 5%。
Tetraethylene glycol dimethyl ether was synthesized by an improved Williamson reaction with tetraethylene glycol, methyl chloride and alkaline hydroxide at the suitable molar ratio ofn(C 8H 18 O 5)∶n(CH 3Cl)∶n(MOH)=1∶(2-3)∶(2-5). Under the pressure of 0 6 MPa, reacting for 3 h at the temperature 55-90 ℃,the conversion of tetraethylene glycol was greater than 99% and the selectivity of dimethyl ether was 786%.Moreover, the mixed tetraethylene and pentaethylene glycol dimethyl ether was synthesized with the by-product of tetraethylene glycol. The reaction was finished in about 2 h, and the selectivity of dimethyl ether was 935%.
出处
《精细化工》
EI
CAS
CSCD
北大核心
2000年第4期202-204,共3页
Fine Chemicals
