摘要
1,2-苯并-异噻唑啉-3-酮(BIT)与醋酸锌、醋酸铜反应得到配合物[Zn(BIT-H)2](1)及[Cu(BIT)(BIT-H)(CH3COO)](2);通过元素分析、核磁共振、红外光谱和紫外可见分析等手段对配合物结构进行表征。将配合物1和配合物2分别做抑菌实验,它们对大肠杆菌的最小抑菌质量浓度分别为2.344×10-3、1.172×10-3 g/L,对金黄色葡萄球菌的最小抑菌质量浓度分别为5.86×10-4、5.86×10-4 g/L,配合物的抑菌性能很好。
Two organic/inorganic complexes, [ Zn （ BIT-H ） 2 ] （ 1 ） and [ Cu （ BIT ） （ BIT-H ） （ CH3 COO） ] （2）, were obtained from the reaction of 1,2-benzoisothiazolin-3-one （BIT） with copper acetate and zinc acetate. The structures of the complexes were characterized by means of EA, i HNMR, IR and UV-vis. Experiments of the antibacterial activity of the two complexes were conducted and the results were analysed. The MIC of the two complexes with Escherichia coli were：2. 344 × 10^-3 g/L, 1. 172 × 10^-3 g/L,and the MIC of the two complexes with Staphylococcus aureus were：5.86 ×10^-4 g/ L,5.86 × 10^ -4 g/L, showing that the complexes possess excellent antibacterial activity.
出处
《精细化工》
EI
CAS
CSCD
北大核心
2012年第7期641-645,共5页
Fine Chemicals
基金
国家高技术研究发展计划(863计划)资助(2010AA09Z203和2010AA065104)
海洋公益性行业科研专项经费资助(201005028-2)~~
